Performance of Bipolar Disorder Patients in Attention Testing: Comparison with Normal Controls and Among Manic, Depressive, and Euthymic Phases

Abstract

Several studies on cognition in bipolar disorder (BD) have been developed on the last decade. Neuropsychological evaluation of attention in BD patients is fundamental since alterations in attention affect other cognitive functions. Evaluate if performance of BD patients in attention tests varies according to each phase of the disease and verify if there are differences in attention when comparing BD patients with normal controls. The study included 101 BD patients, with ages between 18 and 65 years, being 52 euthymic, 22 manic and 27 depressive, besides 30 normal controls. All subjects were evaluated though Hamilton Depression Scale, Young Mania Rating Scale and Global Assessment of Functioning, bipolar version (CGI-BP). Attention was evaluated through a neuropsychological battery. Normal controls had a better performance in selective attention tests than BD patients. No differences were found among manic, depressive and euthymic phases. Attention is markedly impaired in BD. Nevertheless, the results of this study do not imply that the severity of the attention deficit in BD patients varies according to decease phase.

Periodontal condition and levels of bacteria associated with periodontitis in individuals with bipolar affective disorders: A case‐control study

“…The multivariate final model revealed that individuals in the depression phase presented 28.0 times more chances of them having periodontitis than individuals in the mania phase. Studies showed that individuals with BPAD are 3 times more frequent in the depression phase than in the mania phase …”

“…One recurrent and serious mental health condition is the bipolar affective disorder (BPAD). Individuals with BAPD have what is called episodes or phases of extreme mania followed by long periods of depression . BPAD is estimated to have a worldwide prevalence rate of 2%‐5% .…”

Alterações Neuropsicológicas no Transtorno Bipolar

“…A avaliação da fase da doença e os sintomas que a mesma apresenta é essencial para a compreensão do transtorno. Camelo et al, (2017) avaliaram se o desempenho dos pacientes com TB nos testes de atenção variava de acordo com cada fase da doença, e se há diferença quando comparados com pessoas que não possuem o transtorno. O estudo foi realizado com 101 pacientes diagnosticados com algum tipo de transtorno, com idade entre 18 e 65 anos, sendo 22 maníacos, 27 depressivos, 52 eutímicos, além de 30 pessoas saudáveis.…”

Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience

“…Another primary link can be delineated between Attention and Thought Disorder, based on studies showing that increased attentional lapses, distractibility, and impairments in attentional task performance are increased across psychotic disorders (Gold et al, 2019;Ivleva et al, 2012a) and associated with symptoms of schizophrenia (Guastella et al, 2013) and positive schizotypy (Marsh et al, 2017;Mohanty et al, 2008;Siddi et al, 2017). The association of attentional lapses and distractibility with manic symptoms further indicates a primary link between Attention and the Mania subfactor (Camelo et al, 2017;Glaus et al, 2018;Pagliaccio et al, 2017), which is provisionally connected to both the Thought Disorder and…”