This work is concerned with the study of the influence of impactor’s velocity parameters, impactor’s geometry, the target plate properties, and thickness, on the response of a tropical wood plastic composite (WPC) Azobé/urea formaldehyde (Az/UF) plate under impact loading. Variations of the impact force, displacement, deformation, and impact energy of the specimens with weight fractions of 10, 20, 30, 40, and 50% have been considered in finite element analysis (FEA) simulations. The simulations of the Charpy and of a drop weight impact test on the WPC were carried out using the explicit dynamics module of ANSYS Workbench, which handles problems of dynamic loading of a short duration for 2D and 3D analyses. Contact laws that account for the compressibility of the interacting bodies (the standard steel impactor and the WPC target plate), have been used. The results show that the displacements decrease in contrast to the increase of the wood filler content, and vary in the 6.8–9.0 mm interval. From an energetic point of view, it is observed that the maximum absorbed energy is between 40 and 50% for the Azobe flour wt.%, with energy absorption rates of 28% and 26% of the total energy. These results are in agreement with those reported in previous experimental investigations on hybrid WPCs filled with wood flour and glass fibers, which produce an energy absorption rate of 24–26%. These results promote the applicability of Azobé tropical wood in fabricating WPCs for impact loading situations.