Performance of Osteoporosis Self-Assessment Tool (OST) in Predicting Osteoporosis—A Review

Subramaniam, Shaanthana; Ima‐Nirwana, Soelaiman; Chin, Kok‐Yong

doi:10.3390/ijerph15071445

Cited by 36 publications

(30 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…34 Thus, appropriate adjustment of optimal cutoff values may improve the efficacy of the OSTA, 36 and revalidating the instrument in accordance with the real conditions among a local population is strongly suggested before using the OSTA for clinical screening for OP. 36,37 FRAX is well known as a prediction tool for the 10year probability of hip fractures (FRAX-HF) and major osteoporotic fractures (FRAX-MOF), 38 and it also has been reported to be an effective tool in screening for OP. 14,39 In our study, the overall AUCs for FRAX without BMD with all diagnostic criteria ranged from 0.728 to 0.855, performing as well as the OSTA in predicting OP.…”

Section: Discussionmentioning

confidence: 99%

Comparison of OSTA, FRAX and BMI for Predicting Postmenopausal Osteoporosis in a Han Population in Beijing: A Cross Sectional Study

Fan¹,

Li²,

Zhang³

et al. 2020

CIA

View full text Add to dashboard Cite

Purpose: To validate the efficacies of three screening tools including the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI) for predicting postmenopausal osteoporosis (OP) and to define the ideal thresholds for avoidance of dual-energy X-ray absorptiometry (DXA) scanning in a Han Chinese population in Beijing. Patients and Methods: A total of 2055 community-dwelling Han Beijing postmenopausal females aged ≥45 years were enrolled in this study. All participants completed a questionnaire, and BMD was measured by DXA. OP was defined by a T-score at least −2.5 SD less than that of average young adults in different diagnostic criteria [lumbar spine, femoral neck, total hip, worst hip, WHO]. The abilities of the OSTA, FRAX, and BMI to predict OP were analyzed by receiver operating characteristic (ROC) curves. Sensitivity, specificity, and area under the ROC curves (AUC) were calculated. Ideal thresholds for identifying OP were proposed. Results: The prevalence of OP ranged from 8.1% to 28.4% according to different diagnostic criteria. The AUC range for the OSTA (0.758-0.849) was similar to the FRAX (0.728-0.855), which revealed that both tools predicted OP reliably. The AUC range for BMI was 0.643-0.682, suggesting limited predictive value. According to WHO criteria, the AUC values for the FRAX for hip fracture risk (FRAX-HF) and for the OSTA were 0.796 and 0.798, with corresponding sensitivities of 74.79% and 69.64% and specificities of 70.45% and 75.07%, respectively. At defined thresholds, the FRAX-HF and OSTA allowed avoidance of DXA in 42.4-37.6% of participants, at a cost of missing only 7.2-8.6% of individuals with OP. Conclusion: The OSTA and FRAX-HF may be reliable and effective tools for identifying postmenopausal OP in the Han Beijing population without BMD.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison of OSTA, FRAX and BMI for Predicting Postmenopausal Osteoporosis in a Han Population in Beijing: A Cross Sectional Study

Fan¹,

Li²,

Zhang³

et al. 2020

CIA

View full text Add to dashboard Cite

show abstract

“…Participants were considered frail if five or more of the above criteria were present. 10,11 Orthostatic Hypotension Systolic (SBP) and diastolic blood pressure (DBP) was measured in clinic according to the European Society of Hypertension guidelines using validated equipment that meets certification criteria. 12 Orthostatic test included measurement of heart rate, SBP and DBP in the sitting position, the supine position, and at 1, 2 and 3 minutes after the transition to a vertical position.…”

Section: Frailtymentioning

confidence: 99%

Association Between Arterial Stiffness, Frailty and Fall-Related Injuries in Older Adults

Turusheva¹,

Фролова²,

Kotovskaya³

et al. 2020

VHRM

View full text Add to dashboard Cite

This study was conducted to investigate the relationships between arterial stiffness, frailty and fall-related injuries among community-dwelling older adults. Materials and Methods: A cross-sectional study of a random sample of older adults aged 60 years and older was conducted. Main study parameters: arterial stiffness was measured by the determining the cardio-ankle vascular index (CAVI); Frailty status was defined using a 7item frailty screening scale, developed in Russia. This questionnaire included question about falls and fall-related injuries. Orthostatic test and anthropometric tests were done. Medical history (comorbidity, medications), the Osteoporosis Self-assessment Tool (OST), nutritional, physical, cognitive and functional status were evaluated. Results: The study population included 163 people aged 60-89 years. The average predicted value of CAVI in women aged 60-69 was 9.13 ± 0.13, in men, 9.49 ± 0.05; in women aged 70-79, it was 9.49 ± 0.16, in men, 9.73 ±0.11; in women aged 80 and older it was 10.04 ±0.18, in men, 10.24 ±0.10 units. The CAVI above the predicted value was associated with fall-related injuries even after adjustment for age, sex, use of β-blockers (BBs), history of stroke, and region of residence with the odds ratio 3.52 (95% CI: 1.03 −12.04). Conclusion: Our study revealed an independent association between arterial stiffness and fall-related injuries in older adults over 60 years. The findings suggest that clinicians, especially geriatricians, should pay attention to arterial stiffness of patients with fall-related injuries. Similarly, the patients with CAVI above age-predicted value should be evaluated for risk of falls for prevention of fall-related injuries.

show abstract

“…Conclusions. Modeling of pathological conditions in the tissues of periodontal and dental pulp on experimental animals enables prediction of changes in the dentoalveolar system in humans upon a significant increase in life expectancy [10,11]. PD and OP, which accompany the aging problem, contribute to reduced quality of life and require changes in medical care for such patients.…”

Section: ключевые слова: остеопороз пародонтит эксперимент эндотелийmentioning

confidence: 99%

The histochemical features of the endothelium of the tooth-alveolar complex in inflammation and osteoporosis

Vladimirivich¹,

Vyacheslavovich²,

Bykov³

et al. 2018

Medical news of the North Caucasus

View full text Add to dashboard Cite

Ставропольский государственный медицинский университет, российская Федерация 2 Кубанский государственный медицинский университет, Краснодар, российская Федерация The results of immunohistochemical studies of the pulpal state and vascular endothelium of the dental alveolar complex are presented in the experimental modeling of periodontitis and osteoporosis in sheep. The endothelial structural parameters of PD in animals in the gums of the upper and lower jaws differ and affect the length, thickness of cells, number of mitochondria, Golgi complex, reticulum of the endothelium, relationship between the nucleus and cytoplasm, and amount of heterochromatin in the nucleus. In periodontitis, pathological changes are noted in the endothelial circle, as well as in pericytes; this is manifested by a complex vascular-tissue reaction of the microcirculatory bed of periodontal tissues with a violation of the rheological properties of the blood, combined with the formation of exudate and an inflammatory cell infiltrate. In the early period after the formation of the model of experimental osteoporosis, slight thickening and straightening were observed in the Korff fibers; at 180 days, the APhF exhibited a more linear structure, occasionally forming a finely mottled network that resembled a mosquito net. At 1 year of observation, there was a lack of Korff fibers in the primary substance of the pulp, and significant thickening of the argyrophilic membranes in the vascular endothelium; these are signs of impairment in the metabolism of the tooth pulp.

show abstract

Performance of Osteoporosis Self-Assessment Tool (OST) in Predicting Osteoporosis—A Review

Cited by 36 publications

References 52 publications

<p>Comparison of OSTA, FRAX and BMI for Predicting Postmenopausal Osteoporosis in a Han Population in Beijing: A Cross Sectional Study</p>

<p>Comparison of OSTA, FRAX and BMI for Predicting Postmenopausal Osteoporosis in a Han Population in Beijing: A Cross Sectional Study</p>

<p>Association Between Arterial Stiffness, Frailty and Fall-Related Injuries in Older Adults</p>

The histochemical features of the endothelium of the tooth-alveolar complex in inflammation and osteoporosis

Contact Info

Product

Resources

About