The spatiotemporal variability of meteorological droughts, its changes and hot spots location across Africa are analysed for the period spanning 1928–2017 using the Standardized Precipitation Index (SPI) applied to the precipitation products from the Climatic Research Unit (CRU), University of Delaware (UDEL) and Global Precipitation Climatology Centre (GPCC). Spatially, an analysis based on rotational empirical orthogonal function identifies five regions of similar drought variability, namely the Sahel, East Africa, East Southern Africa, West Southern Africa and the Gulf of Guinea. Temporally, the most common periods of drought occurrence are the 1970s, the 1980s and, to a lesser extent, the 1990s. Changes in drought characteristics for the intermediate past (1958–1987) and recent past (1988–2017) compared to the far past (1928–1957) indicate robust increases of drought duration, frequency and severity in the Sahel, and to a lower extent in the Gulf of Guinea, some areas of Central Africa, part of Southern Africa and over Madagascar. These changes are stronger (weaker) along the Sahel during the intermediate past (recent past) and stronger (weaker) over Central and Southern Africa and Madagascar during the recent past (intermediate past). As a consequence, drought hot spots, mostly driven by severity during the regions' wet season, are identified in areas confined in the Sahel during the intermediate past and in regions mainly over Central and Southern Africa and Madagascar during the recent past. Our results are useful for drought disaster risk management across Africa and provide a valuable reference for future drought analysis under global warming conditions.