“…During the last decades, numerous studies have demonstrated the benefits of oral TM supplementation on beef cattle immunity, health and performance [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. However, other studies have shown marginal or insignificant effects of oral TM supplementation on beef cattle metabolism, growth, immunity and health [ 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 ]. Many of these studies have provided inconsistent results due to differences in mineral forms supplemented (organic versus inorganic), high variability in TM concentration in control diets, the animals’ TM requirements and initial TM status, variation in animal intake and absorption, chemical mineral interactions and antagonisms, level of stress, and differences in experimental models and endpoints.…”