Performance of the Osteoporosis Self-Assessment Tool for Asians (OSTA) in Screening Osteoporosis Among Middle-Aged and Old Women in the Chengdu Region of China

Huang, Jhin‐Fang; Song, Wenqiang; Zeng, Hui-Rong; Huang, Mei Hua; Wen, Qing

doi:10.1016/j.jocd.2015.01.001

Cited by 22 publications

(20 citation statements)

References 17 publications

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“…In a large epidemiological study involving 15,752 healthy Chinese women aged 40–96 years, Huang et al showed that the performance of OSTA based on AUC and its sensitivity increased with age, but its specificity decreased with age. 22 Similar findings were observed in another study by Huang et al among 11,039 Chinese men with similar age range. 23 This suggests that OSTA is suitable to be used in older subjects with higher risk of osteoporosis compared to younger subjects.…”

Section: Discussionsupporting

confidence: 86%

Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis

Chin¹,

Low²,

Kamaruddin³

et al. 2017

TCRM

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BackgroundCalcaneal quantitative ultrasound (QUS) is a useful tool in osteoporosis screening. However, QUS device may not be available at all primary health care settings. Osteoporosis self-assessment tool for Asians (OSTA) is a simple algorithm for osteoporosis screening that does not require any sophisticated instruments. This study explored the possibility of replacing QUS with OSTA by determining their agreement in identifying individuals at risk of osteoporosis.MethodsA cross-sectional study was conducted to recruit Malaysian men and women aged ≥50 years. Their bone health status was measured using a calcaneal QUS device and OSTA. The association between OSTA and QUS was determined using Spearman’s correlation and their agreement was assessed using Cohen Kappa and receiver-operating curve.ResultsAll QUS indices correlated significantly with OSTA (p<0.05). The agreement between QUS and OSTA was minimal but statistically significant (p<0.05). The performance of OSTA in identifying subjects at risk of osteoporosis according to QUS was poor-to-fair in women (p<0.05), but not statistically significant for men (p>0.05). Changing the cut-off values improved the performance of OSTA in women but not in men.ConclusionThe agreement between QUS and OSTA is minimal in categorizing individuals at risk of osteoporosis. Therefore, they cannot be used interchangeably in osteoporosis screening.

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Section: Discussionsupporting

confidence: 86%

Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis

Chin¹,

Low²,

Kamaruddin³

et al. 2017

TCRM

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“…Its performance (cutoff = −1; sensitivity = 91%; specificity = 45%; AUC = 0.79) was superior than the reported values of the SOFSURF index [ 14 ], Osteoporosis Risk Assessment Index (ORAI), and Simple Calculated Osteoporosis Risk Estimation (SCORE) [ 15 ]. The performance of OSTA was subsequently validated in other East Asian populations, such as Chinese [ 16 ] and Korean women [ 17 ], and comparable results were obtained. This is not surprising, considering that a majority of the subjects in the development phase were East Asians [ 11 ].…”

Section: Performance Of Ost Among Asiansmentioning

confidence: 98%

“…This is not surprising, considering that a majority of the subjects in the development phase were East Asians [ 11 ]. In addition, the validation study by Huang et al (2015) showed that OSTA performed better when BMD at the femoral neck was used as the reference, and when the women tested were older [ 16 ]. The site difference is probably due to the presence of osteophyte at the lumbar spine, which distorts its BMD.…”

Section: Performance Of Ost Among Asiansmentioning

confidence: 99%

Performance of Osteoporosis Self-Assessment Tool (OST) in Predicting Osteoporosis—A Review

Subramaniam

Ima‐Nirwana

Chin

2018

IJERPH

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Bone health screening plays a vital role in the early diagnosis and treatment of osteoporosis to prevent fragility fractures among the elderly and high-risk individuals. Dual-energy X-ray absorptiometry (DXA), which detects bone mineral density, is the gold standard in diagnosing osteoporosis but is not suitable for screening. Therefore, many screening tools have been developed to identify individuals at risk for osteoporosis and prioritize them for DXA scanning. The Osteoporosis Self-assessment Tool (OST) is among the first tools established to predict osteoporosis in postmenopausal women. It can identify the population at risk for osteoporosis, but its performance varies according to ethnicity, gender, and age. Thus, these factors should be considered to ensure the optimal use of OST worldwide. Overall, OST is a simple and economical screening tool to predict osteoporosis and it can help to optimize the use of DXA.

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“…In this developmental study, OSTA performed better than other osteoporotic indices by showing a sensitivity of 91%, specificity of 45%, and receiver operating characteristic curve of 0.79 at the cutoff of −1 [ 17 ]. In addition, at the cutoff of −1, the difference in OSTA performance was minimal regardless of using the femoral neck and lumbar spine BMD as reference [ 20 ]. Based on the OSTA scores, patients could be stratified as with low (OSTA > −1), medium (−1 ≥ OSTA ≥ −4), and high risk (OSTA < −4) for sustaining osteoporosis [ 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

“…According to OSTA score, the risk of osteoporosis is 61%, 15% and 3% for those patients with high-, medium- and low-risk osteoporosis, respectively [ 17 ]. With strong correlations for the populations in Taiwan [ 21 , 24 ], China [ 20 ], Korea [ 25 ], Singapore [ 26 ], Malaysia [ 23 ], Thailand [ 27 ], and Philippines [ 28 ], OSTA has been validated as an effective and feasible screening tool to identify patients at risk for sustaining osteoporosis [ 17 , 18 , 23 , 26 , 28 , 29 , 30 , 31 ].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of Bone Fracture in Female Trauma Patients Based on Risks of Osteoporosis Assessed using the Osteoporosis Self-Assessment Tool for Asians Score

Rau

Kuo

et al. 2017

IJERPH

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Background: Osteoporotic fractures are defined as low-impact fractures resulting from low-level trauma. However, the exclusion of high-level trauma fractures may result in underestimation of the contribution of osteoporosis to fractures. In this study, we aimed to investigate the fracture patterns of female trauma patients with various risks of osteoporosis based on the Osteoporosis Self-Assessment Tool for Asians (OSTA) score. Methods: According to the data retrieved from the Trauma Registry System of a Level I trauma center between 1 January 2009 and 31 December 2015, a total of 6707 patients aged ≥40 years and hospitalized for the treatment of traumatic bone fracture were categorized as high-risk (OSTA < −4, n = 1585), medium-risk (−1 ≥ OSTA ≥ −4, n = 1985), and low-risk (OSTA > −1, n = 3137) patients. Two-sided Pearson’s, chi-squared, or Fisher’s exact tests were used to compare categorical data. Unpaired Student’s t-test and Mann–Whitney U-test were used to analyze normally and non-normally distributed continuous data, respectively. Propensity-score matching in a 1:1 ratio was performed with injury mechanisms as adjusted variables to evaluate the effects of OSTA-related grouping on the fracture patterns. Results: High- and medium-risk patients were significantly older, had higher incidences of comorbidity, and were more frequently injured from a fall and bicycle accident than low-risk patients did. Compared to low-risk patients, high- and medium-risk patients had a higher injury severity and mortality. In the propensity-score matched population, the incidence of fractures was only different in the extremity regions between high- and low-risk patients as well as between medium- and low-risk patients. The incidences of femoral fractures were significantly higher in high-risk (odds ratio [OR], 3.4; 95% confidence interval [CI], 2.73–4.24; p < 0.001) and medium-risk patients (OR, 1.4; 95% CI, 1.24–1.54; p < 0.001) than in low-risk patients. In addition, high-risk patients had significantly lower odds of humeral, radial, patellar, and tibial fractures; however, such lower odds were not found in medium- risk than low-risk patients. Conclusions: The fracture patterns of female trauma patients with high- and medium-risk osteoporosis were different from that of low-risk patients exclusively in the extremity region.

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Performance of the Osteoporosis Self-Assessment Tool for Asians (OSTA) in Screening Osteoporosis Among Middle-Aged and Old Women in the Chengdu Region of China

Cited by 22 publications

References 17 publications

Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis

Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis

Performance of Osteoporosis Self-Assessment Tool (OST) in Predicting Osteoporosis—A Review

Epidemiology of Bone Fracture in Female Trauma Patients Based on Risks of Osteoporosis Assessed using the Osteoporosis Self-Assessment Tool for Asians Score

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