Perfusion index and its dynamic changes in preterm neonates with patent ductus arteriosus

Abstract

Ductal persistence and flow pattern did not affect PI but did affect PVI in preterm neonates of less than 29 weeks of GA. Future studies are needed to establish the usefulness of PVI in the early detection and management of PDA in preterm neonates.

Perfusion Index in Preterm Infants during the First 3 Days of Life: Reference Values and Relation with Clinical Variables

“…Earlier studies have shown conflicting results concerning the effect of hsPDA on PI [20,21]. In the current study, there was a positive association with PI during the first 24 h and from 37 h onwards (when taking into account the hsPDA × time interaction) as also found by others [20].…”

Perfusion index in the preterm infant immediately after birth

“…Hakan et al reported a median PI value of 0.88(0.6, 1.26) in a cohort of 45 preterm infants [14] and Vidal et al found a median PI of 0.70 (0.50, 1.05) in a similar number of preterm infants [15]. We describe slightly higher values in preterm infants immediately after birth, 1.3 (0.86, 1.68).…”

“…It has also been shown that PI is highly reproducible in preterm infants [12], that this value increases over the first 3 days of life [10,13], and that PI may stabilise within 5 days of life [14]. Normative PI values have been described for preterm infants in the first day of life [14,15]. However, to our knowledge, PI values immediately after birth have not previously been determined.…”

Perfusion index in newborn infants: a noninvasive tool for neonatal monitoring

“…Consequently, they propose that the age of the neonates should be taken into account for its clinical application. A study in preterm neonates with a haemodynamically important persistent ductus arteriosus also established different PI values depending on the neonate age that were not influenced by ductal flow pattern, with a median PI value of 0.7% in the first day of life (0.5–1.05%) and 1.5% (1.0–2.0%) on the seventh (p < 0.01). PI has also been proven to vary, specially in very preterm infants, depending on the placement of the pulse oximeter , being higher in the upper limbs (right upper limb = 0.92% vs. lower limb = 0.69%, mean difference = 0.24%, p < 0.001), fact probably related to the transitioning circulation in this population where patent ductus arteriosus is not uncommon, and the position of the low birthweight newborn, presenting a higher PI in prone sleeping position (mean PI value 3.7 ± 0.9% vs. PI 3.1 ± 0.7%).…”