Perfusion of the isolated canine stomach

Salmon, Peter A.; Assimacopoulos, Costas A.

doi:10.1016/s0022-4804(64)80081-0

Cited by 8 publications

(4 citation statements)

References 17 publications

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“…Studies on isolated perfused canine pouches have been conducted by Eisenberg, Shapiro, and Woodward (1963) and Moody, Gilder, and Beal (1962). Salmon and Assimacopoulos (1964) reported on various types of secretory responses in histaminestimulated isolated perfused canine stomachs for 6& hours.…”

Section: Methodsmentioning

confidence: 99%

Secretory response to sustained histamine stimulation of the isolated canine stomach

Dritsas

Bondar

Kowalewski

1966

Journal of British Surgery

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Section: Methodsmentioning

confidence: 99%

Secretory response to sustained histamine stimulation of the isolated canine stomach

Dritsas

Bondar

Kowalewski

1966

Journal of British Surgery

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“…Perfusion Apparatus.-The extracorporeal circuit consisted of an arterial and a venous Gibbon-Mayo roller pump with an attached flow calibration device, a constant-temperature perfusion chamber similar to that used by others (Salmon and Assimacopoulos, 1964), an air-tight venous reservoir, and a dog anaesthetized and heparinized to serve as an oxygenator.…”

Section: Rg Eamentioning

confidence: 99%

“…Motility studies have been conducted on the isolated canine stomach supported by the neck vessels of a donor dog (Kawasaki, 1940). The longest known functional survival time of the intact isolated stomach is the 64 hours reported by Salmon and Assimacopoulos in 1964. These investigators believe their success is the result of adaptation of an extracorporeal circuit primed with autologous blood, oxygenated with an autologous lung lobe.…”

mentioning

confidence: 99%

Perfusion of the isolated canine stomach

Dritsas

Kowalewski

1966

Journal of British Surgery

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artery can be drawn from the pulse or the pressure within it. SUMMARY I. Direct measurement of arterial flow is desirable. At present, electromagnetic flowmeters appear to be the best instruments for this, but are still beset with difficulties.2. Contrary to the usual assumption, pulse, pressure, and temperature are not directly related to arterial flow.3. 'Teflon' prostheses and vein grafts of a narrowing shape were inserted in dogs to by-pass arterial occlusions. Whether the blood entered at the wide or the narrow end did not make any appreciable difference to the resulting flows and pressures.4. The presence of a pulse beyond an arterial obstruction may have an apparently paradoxical relation to the distal flow. It has been confirmed by experiment in dogs that such a pulse may disappear as flow improves and distal pressure rises, and may reappear as flow decreases and distal pressure falls as the result of distal obstruction.

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“…Isolated perfusion preparations are useful, but pose many technical problems. 1 Although total, or partial stomach trans¬ plantation experiments and experiments of isolated gastric perfusions are not recent de¬ velopments, the results have never been completely satisfactory.2·3 With the recent development of a technic which facilitates the anastomosis of small vessels, however, the number of stomach transplantation ex¬ periments undertaken has increased.4 9 In the study of homotransplantation of the dis¬ tal half of the stomach by Thompson (6V2 hours) * The method reported here combines fea¬ tures of both transplantation and isolated stomach perfusion, and has proven to date to be a practical approach to the study of gastric physiology.…”

mentioning

confidence: 99%