Perianal ulceration: a case of tuberculosis cutis orificialis

León-Mateos, A.; Sánchez‐Aguilar, D.; Lado, F. L. Lado; Toribio, J.

doi:10.1111/j.1468-3083.2004.01147.x

Cited by 18 publications

(10 citation statements)

References 31 publications

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“…Lin et al 13 described a patient with angioimmunoblastic T-cell lymphoma who developed perianal tuberculosis during the neutropenic phase after chemotherapy. Table 2 summarizes the differential diagnosis of TCO with perianal involvement [14][15][16] . Of these diagnoses, Crohn's disease is the most important entity within the differential diagnosis.…”

Section: Discussionmentioning

confidence: 99%

A Case of Tuberculosis Cutis Orificialis with Perianal Involvement

Choi

Kim

2009

Ann Dermatol

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Tuberculosis cutis orificialis (TCO) is a rare manifestation of cutaneous tuberculosis that is caused by auto-inoculation of mycobacteria in patients with advanced internal tuberculosis. TCO occurs in oral, perianal, or genital mucosa and adjacent skin. The tongue is the most frequently affected site, but the perianal area can also be affected. A 39-year-old male presented with a 4-month history of painful ulcers on the perianal area. The histopathologic findings revealed granulomatous infiltrates composed of epithelioid cells and Langhans-type giant cells in the dermis, and a few acid-fast bacilli noted on Ziehl-Neelsen staining. The polymerase chain reaction (PCR) was positive for Mycobacterium tuberculosis and the chest X-ray showed findings consistent with active pulmonary tuberculosis in both upper lung zones. The skin lesion showed complete resolution 2 months after the start of treatment with antituberculosis agents. We report a case of TCO with perianal involvement in a patient with underlying active pulmonary tuberculosis. (Ann Dermatol 21(4) 443∼446, 2009)

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Section: Discussionmentioning

confidence: 99%

A Case of Tuberculosis Cutis Orificialis with Perianal Involvement

Choi

Kim

2009

Ann Dermatol

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“…Tuberculosis cutis orificialis usually results from autoinoculation of the infectious agent in patients with advanced internal tuberculosis of the lungs, gastrointestinal or genitourinary tract (Leon-Mateos et al, 2005;Ghosh et al, 2009). Haematogenous or lymphatic dissemination from another active source of tuberculosis has also been described (Miteva and Bardarov, 2002).…”

Section: Discussionmentioning

confidence: 98%

Recurrent non-healing perianal ulcer: A case of tuberculosis cutis orificialis

Attas

Ahsan

Hannani

et al. 2015

Journal of Dermatology & Dermatologic Surgery

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Tuberculosis cutis orificialis (TCO) is a rare manifestation of cutaneous tuberculosis. Due to its variable clinical features, the diagnosis may be missed at the onset of the disease. Here we describe, TCO as well as intestinal tuberculosis in a patient with recurrent non-healing perianal ulcer. First TCO was detected, later on intestinal T.B was also detected. The perianal lesions appeared as multiple outbreaks of ulcer which resolved totally after combined anti T.B treatment. The clinical course of intestinal lesions and tuberculosis cutis orificialis appeared interrelated. Ó 2014 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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“…[1–4] Diagnosis and treatment can be delayed in this type of tuberculosis as the differential diagnosis includes a large spectrum of diseases. An asymptomatic pulmonary tuberculosis case presenting with perianal ulceration, initially mistaken for a herpetic ulcer and Crohn’s disease, is reported here.…”

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confidence: 99%

“…[1–4] Periorificial tuberculosis results from autoinoculation of M. tuberculosis in patients with pulmonary, intestinal or genitourinary tuberculosis and manifests as oral, genital or anal ulcerations. [1] The bacilli are thought to reach and attack the traumatized mucosa or skin in swallowed sputum in cases of pulmonary tuberculosis. [23] Rarely, it can occur as a result of hematogenous, lymphatic or direct spread of the disease.…”

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confidence: 99%