“…The half-life is approximately 2 hours, and the effects can be seen within 3 to 4 hours; this is dependent on the dose administered. Therapy with rFVIIa prevented bleeding in patients with liver disease undergoing liver biopsy [29] and other invasive procedures, such as injection of hepatocellular carcinoma, colonoscopic polypectomy, intracranial pressure monitor placement, pericardiocentesis, or pancreatic aspiration [26,[30][31][32]. Therapy with rFVIIa prevented bleeding in patients with liver disease undergoing liver biopsy [29] and other invasive procedures, such as injection of hepatocellular carcinoma, colonoscopic polypectomy, intracranial pressure monitor placement, pericardiocentesis, or pancreatic aspiration [26,[30][31][32].…”