Pericarditis Revealing Large Vessel Vasculitis

Couturier, Bruno; Huyge, Valérie; Soyfoo, Muhammad Shahnawaz

doi:10.5402/2011/648703

Cited by 7 publications

(5 citation statements)

References 3 publications

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“…Our study showed a significant interaction between GCA, pericarditis, and younger age (age < 70 years). These findings correspond well with most case reports and case series previously published on the subject . However, several articles have reported cases of adults age > 70 years with simultaneous presentations of both GCA and pericarditis, which usually regressed after corticosteroid treatment .…”

Section: Discussionsupporting

confidence: 91%

“…These findings correspond well with most case reports and case series previously published on the subject. 8,9,19,[28][29][30][31] However, several articles have reported cases of adults age > 70 years with simultaneous presentations of both GCA and pericarditis, which usually regressed after corticosteroid treatment. 12,32-36 A Spanish case report described a 76-year-old female patient with pectoral girdle pain and a pleural effusion on x-ray who was eventually diagnosed with polymyalgia rheumatica (PMR) accompanied by pleuropericarditis and whose high levels of CA-125 indicated serosal involvement, rather than malignancy.…”

Section: Discussionmentioning

confidence: 99%

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Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

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Background Giant cell arteritis (GCA) is an inflammatory disease of unknown etiology affecting adults age > 50 years. GCA (also known as temporal arteritis) is a vasculitis of large and medium‐size vessels that involves the extracranial branches of the carotid artery. Common manifestations include constitutional symptoms, headache, jaw claudication, scalp tenderness, and vision loss. Cardiac involvement in GCA is considered to be as low as 5%, and < 30 cases of pericarditis among GCA patients have been reported in the literature. The aim of this study was to evaluate the association between GCA and pericarditis by conducting a cross‐sectional study utilizing the database of the largest healthcare provider in Israel. Hypothesis GCA is associated with pericarditis. Methods The proportion of past documentation of pericarditis among patients diagnosed with GCA was compared with that of their age‐ and sex‐matched controls. Univariate analysis was performed using the χ2 and t tests; multivariate analysis was performed using logistic regression. Results The study included 4329 GCA patients and 21 611 controls. GCA patients had higher rates of cardiovascular risk factors. Pericarditis was observed in 53 GCA patients and 72 controls (1.22% vs 0.33%, respectively; P < 0.001), significantly higher among GCA patients in comparison with controls. A significant interaction was found between GCA, pericarditis, and young age (<70 years). Conclusions The study showed an independent association between GCA and pericarditis, especially among young patients. Proper screening should be applied whenever a suspicion arises as to the existence of comorbidity in patients with either disease.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

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“…Pericarditis has also been reported [94]. However a recent large population-based cohort study in the UK analysing data on patients with GCA and/or PMR, showed that they were not at an increased risk of coronary diseases (stable angina, unstable angina, myocardial infarction, unheralded coronary death) and cardiac diseases, (heart failure and cardiac arrest) in comparison to age matched controls, regardless of PMR/GCA duration [80].…”

Section: The Cardiovascular Systemmentioning

confidence: 99%

Giant cell arteritis: ophthalmic manifestations of a systemic disease

Smit

O’Sullivan

Mackey

et al. 2016

Graefes Arch Clin Exp Ophthalmol

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“…Constrictive or effusive constrictive pericarditis, an uncommon complication of chemotherapy, can present with mild and diffuse pericardial FDG-uptake [ 94 ]. Additionally, pericarditis associated with increased metabolism of the wall of the large vessels like the thoracic or abdominal aorta can be caused by underlying vasculitis [ 98 , 99 ].…”

Section: Pericarditismentioning

confidence: 99%

Novel Noninvasive Nuclear Medicine Imaging Techniques for Cardiac Inflammation

Kircher

Lapa

2017

Curr Cardiovasc Imaging Rep

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Purpose of ReviewInflammation is a key player in a wide range of cardiovascular and myocardial diseases. Given the numerous implications of inflammatory processes in disease initiation and progression, functional imaging modalities including positron emission tomography (PET) represent valuable diagnostic, prognostic, and monitoring tools in patient management. Since increased glucose metabolism is a hallmark of inflammation, PET using the radiolabeled glucose analog [18F]-2-deoxy-2-fluoro-d-glucose (FDG) is the mainstay diagnostic test for nuclear imaging of (cardiac) inflammation. Recently, new approaches using more specific tracers to overcome the limited specificity of FDG have emerged.Recent FindingsPET imaging has proven its value in a number of inflammatory conditions of the heart including myocarditis, endocarditis, sarcoidosis, or reactive changes after myocardial infarction. In infection-related endocarditis, FDG-PET and white blood cell scintigraphy have been implemented in current guidelines. FDG-PET is considered as nuclear medical gold standard in myocarditis, pericarditis, or sarcoidosis. Novel strategies, including targeting of somatostatin receptors or C-X-C motif chemokine receptor CXCR4, have shown promising results in first studies.SummaryNuclear medicine techniques offer valuable information in the assessment of myocardial inflammation. Given the possibility to directly visualize inflammatory activity, they represent useful tools for diagnosis, risk stratification, and therapy monitoring.

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Pericarditis Revealing Large Vessel Vasculitis

Cited by 7 publications

References 3 publications

Pericarditis among giant cell arteritis patients: From myth to reality

Pericarditis among giant cell arteritis patients: From myth to reality

Giant cell arteritis: ophthalmic manifestations of a systemic disease

Novel Noninvasive Nuclear Medicine Imaging Techniques for Cardiac Inflammation

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