Periductal Stromal Tumor of the Breast: A Case Report and Review of the Literature

Abstract

We present a woman aged 50 years who underwent a Tru-cut biopsy for a BI-RADS 4 lesion on her right breast and received a histopathology diagnosis of a fibroadenoma. In her one year follow-up, the lesion had progressed and she underwent an excisional biopsy. Her final diagnosis was a periductal stromal tumor. Periductal stromal tumor is an extremely rare and different entity from phylloides tumor, which makes appropriate diagnosis difficult in Tru-cut biopsy and care should be taken. Lesion progression of should require a re-biopsy. Their tendency to recur warrants follow-up. We believe that radiologic, pathologic, and clinical correlation is key in decision-making and diagnosis of these tumors.

First Vacuum-Assisted Excision of a Breast Myofibroblastoma

“…They can very often present similarly with common findings on ultrasonography and mammography and can only be distinguished from one another through histopathology. The differential diagnoses for a breast myofibroblastoma include spindle cell carcinomas: a variant of squamous cell carcinomas; periductal stromal sarcomas: a low-grade neoplasm originating from connective breast tissue; and malignant fibrous histiocytomas: tumours arising from the gland or following adjuvant radiotherapy [25, 26]. For instance, granular cell tumours are benign breast tumours that can sometimes cause skin retraction and nipple inversion which are known signs of malignant disease [27].…”