Perinatal care improves the outcome of triplets

Škrablin, Snježana; Kuvačić, Ivan; Kalafatić, Držislav; Peter, Branimir; Gverić-Ahmetašević, Snježana; Letica-Protega, Nevena; Polak-Babić, J

doi:10.1016/s0301-2115(02)00053-2

Cited by 16 publications

(5 citation statements)

References 30 publications

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“…The following neonatal complications were diagnosed by an attending neonatologist: infection on clinical grounds; respiratory distress syndrome later confirmed by a chest X‐ray; and perinatal asphyxia (Apgar score < 7 at 5 minutes) and/or early neurologic signs [15]. Newborns with convulsions and increased spasticity or hypotonia during the early neonatal period (before discharge) were diagnosed as having early neurologic signs, irrespective of the results of neonatal brain ultrasound [8,16]. Intraventricular hemorrhage, periventricular leucomalacia, subependimal hemorrhage, and periventricular echodensities were diagnosed by ultrasound, which has been used routinely since 1985 for all prematurely delivered newborns and all newborns with asphyxia.…”

Section: Methodsmentioning

confidence: 99%

Perinatal factors associated with the neurologic impairment of children born preterm

Škrablin

Maurac

Banović

et al. 2008

Intl J Gynecology & Obste

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Section: Methodsmentioning

confidence: 99%

Perinatal factors associated with the neurologic impairment of children born preterm

Škrablin

Maurac

Banović

et al. 2008

Intl J Gynecology & Obste

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“…Modern obstetric practices and in-hospital prenatal care for at-risk pregnancies have improved newborn overall health and survival (Skrablin et al 2002), but not all at-risk pregnant women have access to those factors that significantly reduce complications, such as prenatal care, antenatal corticosteroids, or hospitalization in a tertiary care facility with in-house neonatal specialists (O'Shea 2008). The combination of antenatal and postnatal factors that contributes most to optimal outcome remains to be determined.…”

Section: Medical Risk Factorsmentioning

confidence: 99%

Extremely Preterm Birth Outcome: A Review of Four Decades of Cognitive Research

Baron

Rey‐Casserly

2010

Neuropsychol Rev

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Premature birth incidence and survival rates are increasing steadily due to advances in obstetric and neonatal intensive care. Those born at the limits of viability are highly at-risk of adverse neurocognitive function over their lifespan, leading to current controversy regarding aggressive resuscitation efforts for these extremely preterm children. However, data from earlier generation cohorts who were born in substantially different eras of neonatal intensive care cannot be relied on to predict outcome of today's newborn. Our review by the crucial variable of birth cohort year shows a changing developmental trajectory in which today's extremely preterm survivor is likely to have fewer severe medical complications, better neurological outcomes, and fewer adverse cognitive late effects. Such data further underscore the importance of concurrently considering medical, familial, socioenvironmental, and neurobiological factors in combination with individual neonatal intensive care center protocols when studying outcomes of the preterm child. This complex, interrelated range of factors directly affects the immature, rapidly developing premature brain. However, ongoing surveillance to detect subsequent delay or impairment and to apply interventional strategies early in the developmental course holds promise for further enhancement of functional outcome.

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“…New tocolytics, such as atosiban, have also been added to traditional betamimetics and magnesium sulfate. However, only a few studies have addressed changes in the perinatal outcomes of triplet pregnancies, and these studies have shown inconsistent results [131415].…”

Section: Introductionmentioning

confidence: 99%

How much have the perinatal outcomes of triplet pregnancies improved over the last two decades?

Kyeong

Shim

et al. 2019

Obstet Gynecol Sci

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Objective This study was conducted to demonstrate the temporal trends in perinatal outcomes of triplet pregnancies over the last two decades. Methods The medical records of patients with triplet pregnancies at two Korean tertiary-care hospitals from 1992 to 2012 were retrospectively reviewed in regard to maternal and neonatal outcomes. The study was divided into two periods for analysis: period I (1992–2001) and period II (2003–2012). Results Over a 21-year period, 65 women with triplet pregnancies and 185 neonates were analyzed. Period II, when compared with period I, was associated with improved maternal outcomes, characterized by a decreased incidence of preeclampsia (31.8% vs. 2.3%, P =0.002) and anemia (68.2% vs. 30.2%, P =0.003) during pregnancy. Regarding neonatal aspects, the composite morbidity of period II was significantly decreased compared with that of period I, as assessed with a generalized estimating equation for logistic regression (26.2% vs. 8.1%, P =0.03). Multivariable analysis revealed that the gestational age at delivery and the period were significantly associated with the composite neonatal morbidity ( P <0.001 and 0.007, respectively). Conclusion Improved neonatal morbidity was associated with a higher gestational age at delivery and with the more recent decade.

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Perinatal care improves the outcome of triplets

Cited by 16 publications

References 30 publications

Perinatal factors associated with the neurologic impairment of children born preterm

Perinatal factors associated with the neurologic impairment of children born preterm

Extremely Preterm Birth Outcome: A Review of Four Decades of Cognitive Research

How much have the perinatal outcomes of triplet pregnancies improved over the last two decades?

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