Perinatal outcome in pregnancies complicated with gestational diabetes mellitus and very preterm birth: case–control study

Abstract

Preterm birth is defined as all births before 37 completed weeks of gestation. Preterm birth can be further sub-divided based on gestational age: extremely preterm (528 weeks), very preterm (28 to 532 weeks) and moderate preterm (32 to 537 weeks). Retrospective observational casecontrol study review (1 year i.e., 2015) is to assess pregnancy outcome among women with gestational diabetes mellitus (GDM) delivering very preterm (28 + 0/7 to 31 + 6/7 weeks of gestation). The study group included all women diagnosed with GDM and were compared to a control group of women delivering at the same gestational age period but without GDM. In all, 30 women were included in the study, of whom 15 were diagnosed with GDM and 15 were not. All women had a cesarean delivery. Neonates of mothers with GDM had higher ponderal index. Birth weight had the positive associations with blood glucose of newborn (r ¼ 0.37, p ¼ 0.047) and term of births (r ¼ 0.52, p ¼ 0.003). Birth weight had the negative associations with maternal systolic pressure (r ¼ À0.7, p50.05), pre-eclampsia (r ¼ À0.6, p50.05) and maternal pre-pregnancy body mass index (r ¼ À0.5, p50.05). There were no differences in mortality or other parameters for neonatal morbidity, including bronchopulmonary dysplasia, prematurity retinopathy, neonatal anemia. According to our data, very preterm delivery occurring in women with GDM does not confer an increased risk for neonatal complications.

Assessment of Adverse Birth Outcomes and Associated Factors among Diabetic Pregnant Mothers Who Delivered at Mettu Karl Hospital, Illubabor Zone, South West Ethiopia-2018

“…Neonatal admission to NICU was 65%; this finding was less than study done Russia [23] showed that 100% neonatal NICU admission but study done in Saudi Arabia [17] which was less than this finding. This difference may be due to neonatal health care strategy they apply.…”

Assessing the risk factors before pregnancy of preterm births in Iran: a population-based case-control study

“…Preterm birth is defined as delivery before the gestational week 37 or day 259 [1–3]. It has been the most concerning complication among pregnant women and affects 10% of all pregnancies.…”

Hypertensive Disorders during Pregnancy and Risk of Bronchopulmonary Dysplasia in Very Preterm Infants

“…This finding is not new, although recent literature on this issue suggests that well-controlled maternal gestational diabetes does not impose an increased risk for infants' BPD. [48][49][50] A limitation of this study is the fact that maintaining peripheral saturations 90 to 95% early and over 95% once 36 weeks may affect generalizability of our results. A significant proportion of the US and other countries centers target 87 to 93% (or thereabouts) prior to 33 to 34 weeks then over 90% afterward, and BPD rates are different among centers that use different criteria.…”