Periodic Leg Movements During Sleep and Sleep Disturbances in Elders

Youngstedt, Shawn D.; Kripke, Daniel F.; Klauber, Melville R.; Sepulveda, Raul S.; Mason, William J.

doi:10.1093/gerona/53a.5.m391

Cited by 69 publications

(27 citation statements)

References 16 publications

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“…17,32 The findings obtained in the present study on associations or co-morbidity of PLMS with some physical and mental conditions are in agreement with those reported from other studies, such as snoring or obstructive sleep apneas 17-19,21,22,33.34 and depressed mood. 15,21,22 In the current study, peptic ulcer appeared as a significant correlate with PLMS, which was not reported in any pervious studies. It is too early, however, to confirm this finding because the number of those with peptic ulcers was small.…”

Section: Discussioncontrasting

confidence: 61%

Periodic Leg Movements during Sleep in Japanese Community-dwelling Adults Based on the Assessments of Their Bed Partners

Doi

Inoue²,

Minowa

et al. 2003

Journal of Epidemiology

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BACKGROUND: There is little known about epidemiologic evidence on periodic leg movements during sleep (PLMS) for the Japanese. The present study was a cross-sectional epidemiologic study to estimate the prevalence of PLMS and examine the associated factors of PLMS in Japanese community-dwelling adults.METHODS: The subjects were 884 with bed partners or bedroom mates of 1,889 Japanese adults aged 20 years and over randomly selected from the general population. The case ascertainment of PLMS was based on the assessments of their bed partners or bedroom mates using the Pittsburgh Sleep Quality Index. Multiple logistic regression analyses were used for investigating the associated factors.RESULTS: The age-adjusted prevalences (95% confidence interval) were 5.8% (4.7-6.8%) and 1.3% (0.8-1.9%) for 1 to 2-times, and 3-times or greater of PLMS per week during the preceding month, respectively. Those with PLMS were more likely to experience difficulty in initiating sleep, snore during sleep, be depressed, and suffer from peptic ulcer. Sex, age, difficulty in maintaining sleep, excessive daytime sleepiness, medication use to aid sleep, and any psychoactive substances (tobacco, alcohol, and caffeine) were not identified as significant associated factors of PLMS.CONCLUSIONS: The results suggest that the prevalence of PLMS in Japanese community-dwelling adults is not so high as those reported from Western countries, and that PLMS is correlated with some sleep and health disturbances. J Epidemiol 2003;13:259-265.

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Section: Discussioncontrasting

confidence: 61%

Periodic Leg Movements during Sleep in Japanese Community-dwelling Adults Based on the Assessments of Their Bed Partners

Doi

Inoue²,

Minowa

et al. 2003

Journal of Epidemiology

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“…In a large study including 78 patients, Hornyak et al [126] observed that PLMS have a low impact on the subjects' perception of sleep quality. Moreover, two studies have shown a lack of correlation between the severity of PLMS and the mean sleep latency on the MSLT in patients with EDS [127,128]. PLMS and arousals are frequently associated.…”

Section: Periodic Limb Movement Disordermentioning

confidence: 99%

Sleep-related movement disorders

Merlino

Gigli

2011

Neurol Sci

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Several movement disorders may occur during nocturnal rest disrupting sleep. A part of these complaints is characterized by relatively simple, non-purposeful and usually stereotyped movements. The last version of the International Classification of Sleep Disorders includes these clinical conditions (i.e. restless legs syndrome, periodic limb movement disorder, sleep-related leg cramps, sleep-related bruxism and sleep-related rhythmic movement disorder) under the category entitled sleep-related movement disorders. Moreover, apparently physiological movements (e.g. alternating leg muscle activation and excessive hypnic fragmentary myoclonus) can show a high frequency and severity impairing sleep quality. Clinical and, in specific cases, neurophysiological assessments are required to detect the presence of nocturnal movement complaints. Patients reporting poor sleep due to these abnormal movements should undergo non-pharmacological or pharmacological treatments.

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“…In addition, PLMS are also found in many other sleep disorders, especially among those involving a dopaminergic impairment [7]such as narcolepsy [8], and REM sleep behaviour disorder [9]. They are also present in sleep apnea syndrome [10]and in a large percentage of uncomplaining subjects, especially with advancing age [7, 11, 12, 13, 14, 15, 16, 17]. Therefore, the diagnostic value of the PLMS index for RLS remains uncertain.…”

Section: Introductionmentioning

confidence: 99%

Sleep Laboratory Diagnosis of Restless Legs Syndrome

et al. 2002

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Polysomnographic recordings and the Suggested Immobilization Test (SIT) are frequently used to support the clinical diagnosis of restless legs syndrome (RLS). The present study evaluated the discriminant power of 5 different parameters: (1) index of periodic leg movements during sleep (PLMS), (2) index of PLMS with an associated microarousal (PLMS-arousal), (3) index of PLM during nocturnal wakefulness (PLMW), (4) SIT PLM index and (5) mean subjective leg discomfort score during the SIT (SIT MDS) in 100 patients with idiopathic RLS and 50 healthy control subjects. Both groups differed significantly on each parameter studied. Furthermore, while the SIT PLM, the PLMS and the PLMS-arousal indices revealed a poor ability to discriminate patients from controls, the PLMW index and the MDS both showed high sensitivity (87 ± 7 and 82 ± 8, respectively) and specificity (80 ± 11 and 84 ± 10, respectively) for diagnosing RLS. The combination of these 2 parameters correctly classified 88% of all subjects with a sensitivity of 82% and a specificity of 100%.

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Periodic Leg Movements During Sleep and Sleep Disturbances in Elders

Cited by 69 publications

References 16 publications

Periodic Leg Movements during Sleep in Japanese Community-dwelling Adults Based on the Assessments of Their Bed Partners

Periodic Leg Movements during Sleep in Japanese Community-dwelling Adults Based on the Assessments of Their Bed Partners

Sleep-related movement disorders

Sleep Laboratory Diagnosis of Restless Legs Syndrome

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