Periodontal Health and Systemic Conditions

Abstract

According to the new classification proposed by the recent 2017 World Workshop on Periodontal and Peri-implant Diseases and Conditions, periodontitis, necrotizing periodontal diseases, periodontitis as a manifestation of systemic diseases, and systemic diseases or conditions affecting the periodontal supporting tissues, are considered as separate entities. Scientific evidence has demonstrated that periodontal diseases are not just simple bacterial infections but rather complex diseases of multifactorial complexity that interplay with the subgingival microbes, the host immune, and inflammatory responses. Despite dental plaque biofilm being considered the primary risk factor for periodontitis in the vast majority of patients that dentists encounter on a daily basis, there are other factors that can also contribute and/or accelerate pathologic progressive attachment loss. In this article, the authors aim to briefly review and discuss the present evidence regarding the association between periodontal diseases and systemic diseases and conditions.

Periodontitis as a Risk Factor for Breast Cancer – What We Know Till Date?

“…The indirect route supports the theory that chronic periodontitis, that involves inflammatory pathways, may play a active role in other pathological conditions where inflammation is a major mechanism (Linden et al, 2008;Paraskevas et al, 2008). This route is strongly supported by the role of C-reactive protein in this underlying pathogenesis (Lim et al, 2020). Some studies have reported a possible link between chronic periodontal disease and different types of cancer.…”

“…Chronic periodontal disease can contribute to various systemic diseases via a direct and indirect route (Lim et al, 2020). Ulceration in the lining of periodontal pockets that might become a route for bacteria into the systemic circulation and eventually leading to bacteremia that facilitates the periodontal pathogens to settle in distant organs, and thus, precipitating the underlying existing diseases is the direct route (Ohki et al, 2012).…”

“…Thus, the dynamic balance between different bacterial taxa is an important determinant in periodontal disease activity (Graves et al, 2019). Many studies have claimed an existence of a unique set of 'periodontal pathogens' that includes Aggregatibacter actinomycetemcomitans, Prevotella intermedia, P. nigrescens, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Parvimonas micra, Fusobacterium nucleatum, and Campylobacter rectus (Tuominen and Rautava, 2021;Lim et al, 2020).…”

Sosialisasi Infografis Kesehatan Gigi dan Mulut Pada Masa Pandemi di Kelurahan Sungai Ulin

“…Menurut Sabbah (2019) kesehatan gigi dan mulut dapat menentukan kondisi sistemik seseorang (Sabbah et al, 2019). Terdapat penelitian yang menyatakan bahwa penyakit periodontal berhubungan dengan penyakit kardiovaskular, tekanan darah tinggi, stroke, diabetes, penyakit respirasi, bahkan kematian (Fernandez-Solari et al, 2015;Lim et al, 2020;Preshaw et al, 2012). Apabila Kesehatan gigi dan mulut terjaga, maka kesehatan seluruh tubuh juga ikut terjamin.…”

Isolation and identification of the oral bacteria and their characterization for bacteriocin production in the oral cavity

“…The inhabitant organisms would have less probability of surviving in the environment which is pathological to the hosts. This type of situation where resident microbes loses homeostasis leads to onset of several oral diseases such as caries and periodontitis ( Sharma et al, 2018 , Albandar et al, 1999 , Lim et al, 2020 , Costalonga and Herzberg, 2014 , Gotsman et al, 2007 ).…”