Periodontal Manifestations of Adult Onset of Histiocytosis X

Abstract

Histiocytosis X, a reticuloendothelial disorder, includes the three clinical syndromes: Letterer-Siwe and Hand-Schuller-Christian diseases and eosinophilic granuloma of the bone. Twenty-eight cases of adult onset of histiocytosis X involving the head and neck region were found in the literature during the past 20 years; 15 cases were confined to this area, out of which 13 involved jaw bones. Characteristic signs and symptoms of periodontal disease were observed in 22 out of 28 cases (79%) with the lower molar area as a predominant site. A case report of a non-osseous chronic disseminated histiocytosis X with periodontal involvement is presented. The importance of histiocytosis X, as an entity that should be kept in mind as a differential diagnosis of a process where destructive periodontitis is involved, is discussed.

Oral Cavity and Systemic Diseases—Langerhans Cell Histiocytosis

“…it can affect bones without internal involvement. it seems to be more frequent in males than in females with a reported ratio ranging from 1.1:1 to 4:1 (2,3,5,14).…”

“…correct mucosal and periodontal treatment include: tartar removal, and radicular scaling and planing, as well as rigorous hygiene and maintenance to conserve both the teeth and the periodontal tissue (2,10,15,13). An alternative treatment approach for the localized musocal lesion is intralesional steroid injection (13).…”

“…the etiology is unknown and various theories have been proposed, e.g. a role for environmental, infectious, immunologic, genetic causes, and it has even been suggested that lch is a neoplastic process (2,15).…”

Histiocytose à cellules de Langerhans : suivi à long terme de deux cas à localisation faciale traités par chirurgie exclusive

“…• une parodontite agressive entraînant des migrations dentaires (51,2 %), des résorptions radiculaires (17,1 %) ou la perte de dents [20,21] , • des ulcérations ou la mauvaise cicatrisation d'un site d'extraction, • une forte halitose, • des hémorragies gingivales spontanées, • des paresthésies labiales inférieures ou un signe de Vincent [22] , …”

Skeletal Langerhans Cell Histiocytosis Presenting After Periodontal Disease and Diabetes Insipidus: A Case Report

“…Several authors have focussed on periodontal and gingival disease in LCH [13][14][15][16][17] because the incidence of oral lesions is high -77% has been quoted [17], though Annibali et al (2009) described a series of 31 LCH patients of whom 12 (namely 39%) developed oral lesions [16]. When oral lesions and DI co-exist in the same patient, there should be a strong index of suspicion for LCH.…”