Periodontitis is associated with oral health‐related quality of life in individuals with end‐stage renal disease

Abstract

Aim The aim of the present study was to evaluate whether periodontitis is independently associated with oral health‐related quality of life (OHRQoL) in individuals with end‐stage renal disease (ESRD). Materials and Methods Calibrated examiners assessed 180 adults with ESRD. A full‐mouth periodontal examination was performed at six sites on each tooth. Periodontitis was considered a categorical variable (absent, mild/moderate or severe). OHRQoL was assessed using the simplified version of the Oral Health Impact Profile (OHIP14) questionnaire. Adjusted multivariate Poisson regression analysis was used with a conceptual hierarchical approach to calculate the rate ratio (RR) of OHIP14 scores for periodontitis according to the severity categories. Results In the adjusted model, mild/moderate and severe periodontitis were significantly associated with poorer OHRQoL compared to the absence of periodontitis [RR = 1.49 (95% confidence interval: 1.16–1.91) and RR 1.77 (95% CI: 1.36–2.30), respectively]. The adjusted domain‐specific analysis revealed that mild/moderate periodontitis significantly impacted the psychological disability domain and severe periodontitis significantly impacted the physical pain, psychological discomfort, physical disability and psychological disability domains. Conclusions Periodontitis exerts an influence on OHRQoL in individuals with ESRD, with a more severe condition impacting different domains.

Oral health-related quality of life in adult patients with end-stage kidney diseases undergoing renal replacement therapy – a systematic review

“…Accordingly, the effect of psychosocial impact might be explained by a combination of RRT and oral health related issues. This assumption is supported by the strongest association between psychosocial impacts with dialysis duration and periodontitis severity, as presented in two included studies [24,27]. The OHRQoL of patients under RRT appears to be complex and potentially influenced by different disease and oral health-related parameters (Fig.…”

“…Therefore, a sufficient, inflammation-free periodontal situation of patients under RRT should be a clinical goal. Only five studies confirmed an impact of periodontal parameters on the OHRQoL of patients under RRT [18,19,24,25,27]. These results suggest that some patients did not perceive their insufficient periodontal situation as a problem.…”

“…In general, the included studies showed heterogeneous oral health findings for different parameters. The studies that examined periodontal parameters showed a remarkable periodontal burden or periodontal treatment need [17][18][19][20][23][24][25][26][27]. This finding is relevant because periodontal inflammation can be related to an increased risk of bacteraemia and thus systemic infections [39] or pneumonia caused by aspiration of periodontal bacteria [35].…”

Impacto da doença periodontal na qualidade de vida: uma revisão integrativa

“…Os resultados mostram que a doença periodontal causa um impacto negativo na qualidade de vida relacionada à saúde oral (Al-Kattan et al, 2019;Ansari Moghadam et al, 2015;El Tantawi & AlAgl, 2017;Eltas et al, 2016;Fuller et al;Geevarghese et al, 2017;Goel & Baral, 2017;Göktürk & Uçan Yarkaç, 2018;He et al, 2018;Holde et al, 2018;Irani et al, 2015;Karaaslan & Dikilitas, 2019;Levin, Zini, Levine, Weiss, Lev, Taub, et al, 2018;Levin, Zini, Levine, Weiss, Lev, Hai, et al, 2018;Liang et al, 2020;Llanos et al, 2018;Maia et al, 2018;Masood et al, 2019;Meusel et al, 2015;Musurlieva & Stoykova, 2015;Nayak et al, 2017;Oliveira et al, 2020;Passos-Soares et al, 2018;Rebelo et al, 2016;Rekhi et al, 2016;Schmalz et al, 2018;Ustaoglu et al, 2019;Wellapuli & Ekanayake, 2016;Wright et al, 2017;Yaacob et al, 2019;Yadav et al, 2019). Além disso, a doença foi associada a uma diminuição na qualidade do sono (Karaaslan & Dikilitas, 2019), e quanto mais severa era a destruição periodontal, pior era a qualidade de vida (Fuller et al;Göktürk & Uçan Yarkaç, 2018;He et al, 2018;Karaaslan & Dikilitas, 2019;Levin, Zini, Levine, Weiss, Lev, Hai, et al, 2018;…”

Association between Uremic Toxin Concentrations and Bone Mineral Density after Kidney Transplantation

“…Advanced periodontitis can lead to a decline in chewing ability, word pronunciation, and aesthetic function [ 51 ]. This altered qualify of life particularly affects patients with ESKD, as highlighted by Oliveira et al’s finding that mild/moderate periodontitis and severe periodontitis were significantly associated with poorer oral-health-related quality of life, relative to the absence of periodontitis (risk ratio (95% confidence interval) = 1.49 (1.16–1.91) and 1.77 (1.36–2.30), respectively) [ 52 ]. Thus, periodontal disease must be screened and managed in this population–especially since treatment is associated with a reduction in systemic inflammation [ 53 ] and an increase in the glomerular filtration rate [ 54 ].…”