Perioral dermatitis

Wollenberg, Andreas; Bieber, Thomas; Dirschka, Thomas; Luger, Thomas A.; Meurer, Michael; Proksch, Ehrhardt; Schön, Michael P.; Schwarz, Thomas; Thaçi, Diamant; Zuberbier, Torsten; Werfel, Thomas

doi:10.1111/j.1610-0387.2010.07329.x

Cited by 10 publications

(15 citation statements)

References 30 publications

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“…The soothing fluid seems to be more inert than the vehicle cream. Pimecrolimus cream (1%) is a well-recognized treatment for POD and recommended in the current guidelines for POD6. As there are no clinical trial data comparing pimecrolimus cream (1%) with a soothing fluid, we decided to compare published historical data of both treatment regimens.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The choice of a treatment regimen is based more on expert opinions than on clinical trials6. The first guideline for POD treatment comments on several treatment options but does not recommend a single "gold standard" therapy6. The discontinuation of all topical agents (or zero therapy) is an established approach; however, the initial exacerbation of POD regularly hinders patient compliance6.…”

Section: Introductionmentioning

confidence: 99%

“…The first guideline for POD treatment comments on several treatment options but does not recommend a single "gold standard" therapy6. The discontinuation of all topical agents (or zero therapy) is an established approach; however, the initial exacerbation of POD regularly hinders patient compliance6. Topical antibiotics such as metronidazole and erythromycin or topical pimecrolimus are established treatment options despite having a possible rebound effect.…”

Section: Introductionmentioning

confidence: 99%

“…Topical antibiotics such as metronidazole and erythromycin or topical pimecrolimus are established treatment options despite having a possible rebound effect. Systemic agents such as tetracycline or erythromycin derivatives are recommended in severe or recurrent cases6.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy and Safety Results of a Drug-Free Cosmetic Fluid for Perioral Dermatitis: The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) Study

et al. 2014

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BackgroundPerioral dermatitis (POD) is a common inflammatory skin disease without standard therapy.ObjectiveWe sought to evaluate the clinical value of a soothing fluid for the treatment of POD.MethodsWe included 51 patients with POD in this 8-week clinical trial. The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) study had an open-label design and involved twice-daily application of Toleriane Fluide, a soothing cosmetic fluid. Clinical assessment of POD was performed with a predefined questionnaire including the POD severity index (PODSI). Control visits were made after 4 and 8 weeks of treatment.ResultsThe results were compared with those of a historical control group treated with a vehicle cream. Patients treated with the soothing fluid showed a continuous and significant improvement of the PODSI over time. The improvement of PODSI observed with the soothing fluid was better, but not significantly better, than that observed in the historical controls. In addition, the subjective complaints of patients such as disease burden, itching, distension of the skin, and appearance improved during treatment.ConclusionA soothing fluid could be a clinically useful treatment option for POD.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Efficacy and Safety Results of a Drug-Free Cosmetic Fluid for Perioral Dermatitis: The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) Study

et al. 2014

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Erythematous facial papules and pustules in an 8‐year‐old girl

Seitz

Paasch

Paasch³

et al. 2017

J Deutsche Derma Gesell

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Compounded preparations in dermatology – analysis of prescribing habits in everyday clinical practice in Germany

Salzmann¹,

Salzmann

Staubach

2020

J Deutsche Derma Gesell

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Background: Compounded preparations (CPs) are an indispensable addition to approved, commercially available drugs (CADs), especially for topical therapy. In Germany, about eight million CPs are prescribed within the statutory health insurance system each year, 50 % thereof by dermatologists. Methods:We analyzed prescribing habits based on a questionnaire sent out to 186 office-based dermatologists and 1,491 pharmacies in the federal states of Rhineland-Palatinate and Saarland. The goal was to improve patient care by collecting and categorizing data in terms of prescription practice and associated challenges in interdisciplinary cooperation.Results: Overall, 351 pharmacists (23.5 %) and 53 dermatologists (28.4 %) participated in this survey. The most common reason (83 %) stated for prescribing a CP was the possibility to prescribe large quantities of a given topical medication; CPs were most commonly prescribed for psoriasis and various types of dermatitis. The most frequently prescribed active pharmaceutical ingredients were triamcinolone (80 %), erythromycin (78.3 %) and clotrimazole (72.5 %). Fifty-eight percent of pharmacists reported that the collaboration with dermatologists was "associated with problems"; 34 % complained about insufficient communication.Conclusions: CPs are essential for optimizing patient care. Interdisciplinary cooperation poses a challenge to both physicians and pharmacists. In this context, it is important to increase collaborative efforts in terms of training and continuing medical education. Further studies on CPs are required to better elucidate the challenges and opportunities associated with their prescription.

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Perioral dermatitis

Cited by 10 publications

References 30 publications

Efficacy and Safety Results of a Drug-Free Cosmetic Fluid for Perioral Dermatitis: The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) Study

Efficacy and Safety Results of a Drug-Free Cosmetic Fluid for Perioral Dermatitis: The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) Study

Erythematous facial papules and pustules in an 8‐year‐old girl

Compounded preparations in dermatology – analysis of prescribing habits in everyday clinical practice in Germany

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