Periorbital necrotising fasciitis.

Suharwardy, J

doi:10.1136/bjo.78.3.233

Cited by 13 publications

(3 citation statements)

References 6 publications

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“…Unlike NF of the extremities and trunk where cultures are polymicrobial, the causative organism in periorbital infection (table 2) appears to be β-haemolytic Streptococcus7 10 11 14–16 19 20 23 24 26–28 31–35 37 39–42 45 47 48 51–53 55 56 61 63 70 73 74 (mainly S. Pyogenes ) alone but occasionally in combination with S. aureus 7 17 18 25 32 35 38 44–46 49 50 54 55 57 64. Rare causative agents include S. aureus alone,12 59 66 68 72 Pseudomonas aeruginosa ,62 67 Moraxella catarrhalis 65 and Cryptococcus neoformans 4 mainly in the setting of immunosuppression.…”

Section: Resultsmentioning

confidence: 99%

Periorbital necrotising fasciitis

Lazzeri

Figus

et al. 2009

British Journal of Ophthalmology

109

141

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Necrotising fasciitis involving the periorbita is a devastating infection. Potential outcomes range from severe disfigurement, loss of the eye and even to death. Early recognition is critical, although its initially non-distinctive appearance frequently delays diagnosis and treatment. Herein, the authors have performed a systematic review of previously published cases including clinical features, diagnoses and differential diagnoses, pathological characteristics and management. Periorbital necrotising fasciitis is seen mainly in adults with a female predominance (54%); about one-half (47%) of the patients were previously healthy. The infection can follow local blunt trauma (17%), penetrating injuries (22%) and face surgery (11%), but in about one-third of cases (28%) no cause was identified. Non-specific erythema and localised painful swelling of the eyelids characterise the earliest manifestation of the disease, followed by formation of blisters and necrosis of the periorbital skin and subcutaneous tissues. The causative organism in periorbital infection was mainly β-haemolytic Streptococcus alone (50%), occasionally in combination with Staphylococcus aureus (18%). The overall mortality rate was 14.42%. The main risk factor for mortality was the type of causative organism, since all reported cases of death were caused by β-haemolytic Streptococcus alone or associated with other organisms. Unlike necrotising fasciitis affecting other body sites, there was not a strong correlation with age >50 years or the presence of associated chronic illness. Management of periorbital necrotising fasciitis is then based on early distinction of symptoms and signs and aggressive multidisciplinary treatment. Thus, the delay between initial debridement and initiating parenteral broad-spectrum antibiotic therapy should be considered the most critical factor influencing morbidity and mortality.

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Section: Resultsmentioning

confidence: 99%

Periorbital necrotising fasciitis

Lazzeri

Figus

et al. 2009

British Journal of Ophthalmology

109

141

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“…[3][4][5][6][7][8][9][10][11] Most of these reported infections have been associated with immunosuppressive disorders, alcoholism, polymyositis, trauma, or postsurgical exposure. [3][4][5][6][7][8][9][10][11][12] Etiologically, periorbital necrotizing fasciitis can be an aerobic, anaerobic, or polymicrobial infection, with the vast majority of bacteria isolates being group A ␤-hemolytic streptococci and/or Staphylococcus aureus. [1][2][3] There has been one case report each of Enterobacter diversus, Streptococcus viridans, Cryptococcus neoformans, and Pseudomonas aeruginosa causing periorbital necrotizing fasciitis.…”

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Periorbital Necrotizing Fasciitis

Elwood

Sommerville

Murray

2007

Plastic and Reconstructive Surgery

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“…Necrotizing fasciitis caused by group A streptococci is known as streptococcal gangrene or hospital gangrene and was described in 1871 [1]. Periorbital necrotizing fasciitis may be associated with sinusitis, but usually without a history of trauma [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Hyperbaric Oxygen as and Adjust to Management of Periocular Necrotizing Fasciitis: A Report of 2 Cases

Strauss¹

2013

Rheumatol Curr Res

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Introduction: Necrotizing fasciitis is a rare but potentially fatal soft tissue infection. It involves rapidly progressive necrosis of fascia and subcutaneous fat often with necrosis of the overlying skin. Patients may have systemic toxicity, characterized by altered mental status, malaise, leukocytosis, fever, chills, and pain. It most commonly involves the trunk, extremities and perineum. It is often associated with minor trauma, surgery, diabetes mellitus, or intravenous drug abuse. Mortality rate range is 20-40%. Early diagnosis and aggressive treatment are essential for preventing tissue loss and increasing survival.

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Periorbital necrotising fasciitis.

Cited by 13 publications

References 6 publications

Periorbital necrotising fasciitis

Periorbital necrotising fasciitis

Periorbital Necrotizing Fasciitis

Hyperbaric Oxygen as and Adjust to Management of Periocular Necrotizing Fasciitis: A Report of 2 Cases

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