Periorbital purpura (raccoon's eyes)

Raccoon Eyes in Amyloidosis

“…‘Raccoon eyes’ occurs due to increased vascular fragility propagated by accumulation of amyloid fibrils. 3 , 4 …”

“…'Raccoon eyes' occurs due to increased vascular fragility propagated by accumulation of amyloid fibrils. 3,4 Kidneys are the most frequently involved organ and are seen in 70-80% of the patients followed by the heart (50-60%). 1 Macroglossia, a pathognomonic sign of this disorder, is seen in only 10% of patients.…”