Peripapillary retinal nerve fiber layer thickness in preeclampsia and eclampsia

Arab, Mohammad; Entezari, Morteza; Ghamary, Hamidreza; Ramezani, Alireza; Ashori, Adele; Mowlazadeh, Arman; Yaseri, Mehdi

doi:10.1007/s10792-017-0718-9

Cited by 13 publications

(11 citation statements)

References 23 publications

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“…They suggested that progressive RNFL atrophy and/or pregnancy-induced edema recovery may contribute to the formation of lower RNFL thickness. 2 We demonstrated that PPRNFL mean and superior values were significantly thicker in HPWG than in NPWG and there was no significant difference in the preeclamptic group before and after delivery in our study.…”

Section: Discussioncontrasting

confidence: 38%

The Role of Optical Coherence Tomography Angiography in Patients With Preeclampsia

Özcan

Güngör

Saygılı

et al. 2022

Retina

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We investigated microvascular changes in the retina and optic disk by comparing the optical coherence tomography angiography findings in preeclamptic patients with those in control groups and also evaluated the preeclamptic patients after delivery. Optical coherence tomography angiography diagnosed decreased deep capillary plexus vessel density values in patients with preeclampsia, but these results improved after delivery.

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Section: Discussioncontrasting

confidence: 38%

The Role of Optical Coherence Tomography Angiography in Patients With Preeclampsia

Özcan

Güngör

Saygılı

et al. 2022

Retina

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“…They speculated that RNFL thickening in patients with preeclampsia might reflect subclinical involvement of the central nervous system [19]. Arab et al reported that the peripapillary RNFL was reduced in women with preeclampsia and eclampsia [20].…”

Section: Discussionmentioning

confidence: 99%

Optical coherence tomography angiography findings in preeclampsia

Çiloğlu

Okçu

Doğan

2019

Eye

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Objectives To investigate vascular density analysis in the superficial (SCP) and deep capillary plexus (DCP), foveal avascular zone (FAZ), peripapillary vascular density analysis (PPCVD), and peripapillary retinal nerve fiber thickness analysis (PPRNFL) using optical coherence tomography angiography (OCTA) in pregnant women with preeclampsia and to compare the obtained values with healthy pregnant and nonpregnant healthy individuals. Methods A total of 98 pregnant women (55 had preeclampsia, 43 were healthy pregnant women) and 38 healthy nonpregnant women of reproductive age were included in the study. The patients were divided into three groups. Group 1 consisted of pregnant women with preeclampsia, group 2 comprised healthy pregnant women without preeclampsia, and group 3 consisted of healthy women who were not pregnant. All participants underwent a comprehensive ophthalmologic examination including OCTA. Results Superficial foveal density (SFD) and deep foveal density (DFD) were lower in group 1 than in group 3 (p = 0.033, p = 0.041, respectively). Deep parafoveal density (DPD), deep temporal density (DTD), and deep superior density (DSD) values were lower in group 1 than in group 2 and group 3 (p = 0.001). PPRNFL superior and mean values were higher in group 1 and group 2 than in group 3 (p = 0.022, p = 0.029, respectively). The mean superior and inferior RPCVD values were significantly higher in group 1 than in group 2 and group 3 (p = 0.001, p = 0.043, and p = 0.001, respectively). Conclusions In preeclampsia, OCTA shows changes in the microvascular structure of the retina, even without retinopathy findings on biomicroscopy examination.

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“…Kara et al [56] stated that the RNFL thickness of PE patients was lower than that of normal pregnant women. Arab et al [57] found that women with sPE or eclampsia had the greatest decrease in the average RNFL thickness around the optic disc. erefore, it can be inferred that elevated blood pressure causes irreversible damage to the microstructure of the retina, even though there are no obvious clinical macroscopic symptoms.…”

Section: Hypertensive Retinopathymentioning

confidence: 99%

Chorioretinal Alterations Induced by Preeclampsia

et al. 2021

Journal of Ophthalmology

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Hypertension during pregnancy, which is essentially a microvascular disease that destroys the end-organ microcirculation, should not be underestimated, as it could lead to organ failure in the kidneys, lungs, and brain. Preassessment of the microcirculatory state through systematic observation of the fundus has been proven to be noninvasive and feasible. Although hypertension in preeclampsia patients will resolve after childbirth, the sticking point is determining the best termination moment. Early diagnosis and treatment can prevent long-term ocular complications and cardiovascular risks for pregnant women in the future. In order to adjust the treatment strategy through more sensitive and precise fundus changes, we comprehensively summarized the common structural changes in the fundus in preeclampsia patients, including changes in the blood vessels, choroid, and retina, as well as the application of quantitative observation for chorioretinal alterations in recent years.

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Peripapillary retinal nerve fiber layer thickness in preeclampsia and eclampsia

Abstract: In relation to the time of pregnancy, peripapillary RNFL reduced in preeclamptic and eclamptic cases as well as in normotensive pregnant women at 2 months postpartum. This reduction was more in the severe forms of pregnancy-induced hypertension.

Cited by 13 publications

References 23 publications

The Role of Optical Coherence Tomography Angiography in Patients With Preeclampsia

The Role of Optical Coherence Tomography Angiography in Patients With Preeclampsia

Optical coherence tomography angiography findings in preeclampsia

Chorioretinal Alterations Induced by Preeclampsia

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