Peripheral and Central Auditory Dysfunction Induced by Occupational Exposure to Organic Solvents

Fuente, Adrián; Slade, Martin D.; Taylor, T. H.; Morata, Thaís C.; Keith, Robert W.; Sparer, Judy; Rabinowitz, Peter

doi:10.1097/jom.0b013e3181bae17c

Cited by 45 publications

(56 citation statements)

References 43 publications

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“…The authors suggest the possibility that the data were underestimated, since the methods used may have failed to detect auditory disorders due to their locations in the auditory system. Workers exposed to combined "noise and solvent mixture," when compared with non-exposed controls, had worse results in CAP tests: Speechin-Silence (SS), PPS 36 , HINT 36,39 , Random Gap Detection (RGD) 36,37,39 and DD 34,36 , but no statistically significant difference was observed for MLD 36 . The results suggest that solvents may be adversely associated with central auditory dysfunction.…”

Section: Low Exposure To Mixturementioning

confidence: 94%

“…In all studies of possible impairment to CANS and listening skills, the results suggested action of solvents on the central auditory pathways, indicating that PTA might not be the only recommended audiological test for this population 17,34,36,37,39 .…”

Section: Low Exposure To Mixturementioning

confidence: 99%

“…The results obtained for pure tone thresholds in investigations of possible CAP disorders related to co-exposure ranged from presence of normality, but with higher thresholds among exposed workers (1, 2, 3 and 6 kHz) 37 to the observation of adverse effects at the frequencies of 1, 2 and 3 kHz 36 , 3-6 kHz and 12-16 kHz, with a higher percentage of HL among more exposed individuals 34 . In the absence of noise, subjects exposed to solvent mixture also showed worse hearing thresholds than those not exposed, at 1, 2, 3 and 8 kHz, with solvent exposure significantly associated with binaural average of audiometric thresholds 39 .…”

Section: Low Exposure To Mixturementioning

confidence: 99%

“…Shifts in audiometric thresholds and increased prevalence and/or probability of OHL were some of the data found among the groups of co-exposure to noise and solvent mixture 17,30,[32][33][34][35][36][37]39 .…”

Section: Low Exposure To Mixturementioning

confidence: 99%

“…Most of the studies mentioned exposure to organic solvent mixtures at levels within local and/or international recommended tolerance limits 8,17,27,[30][31][32][33][34][35][36][37][38] . In those studies, noise exposure levels varied according to compliance with the tolerance limit of 85 dB(A) for an eight-hour working day, recommended internationally.…”

Section: Low Exposure To Mixturementioning

confidence: 99%

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Perda auditiva associada à exposição ocupacional a solventes orgânicos: uma revisão sistemática

Mont'Alverne

Corona

Rêgo

2016

Rev. bras. saúde ocup.

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Introduction: evidences indicate chemicals as potentially otoneurotoxic agents; however, there is no consensus as to the associations between exposure characteristics and the ototoxicity of different chemicals present in industrial environments. Objective: to review the available scientific literature in order to identify studies that point to evidence of association, or non-association, between hearing impairment and occupational exposure to organic solvents. Method: systematic review of the literature, through query on electronic databases, considering only original articles, published from January 1987 to February 2013. Results: thirty-one studies were included in the systematic review. Discussion: studies have confirmed exposure to certain solvents as a risk factor for occupational hearing loss, especially in the presence of noise. Various assessment and classification methods were used regarding cochlear and/or central hearing impairment, contributing to the understanding of the extent of chemical-induced hearing loss as well as to the identification of populations at risk. However, data on appropriate diagnostic procedures, safe levels of chemical exposure and dose-response effect have not yet been fully elucidated.

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Section: Low Exposure To Mixturementioning

confidence: 94%

Section: Low Exposure To Mixturementioning

confidence: 99%

Section: Low Exposure To Mixturementioning

confidence: 99%

Section: Low Exposure To Mixturementioning

confidence: 99%

Section: Low Exposure To Mixturementioning

confidence: 99%

See 3 more Smart Citations

Perda auditiva associada à exposição ocupacional a solventes orgânicos: uma revisão sistemática

Mont'Alverne

Corona

Rêgo

2016

Rev. bras. saúde ocup.

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Effects of combined exposure to metals, solvents, and noise on permanent threshold shifts

Schaal

Slagley

Zreiqat

et al. 2017

American J Industrial Med

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Occupational noise exposure and hearing: a systematic review

Lie

Skogstad

Johannessen

et al. 2015

Int Arch Occup Environ Health

321

202

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PurposeTo give a systematic review of the development of noise-induced hearing loss (NIHL) in working life.MethodsA literature search in MEDLINE, Embase, Web of Science, Scopus, and Health and Safety Abstracts, with appropriate keywords on noise in the workplace and health, revealed 22,413 articles which were screened by six researchers. A total of 698 articles were reviewed in full text and scored with a checklist, and 187 articles were found to be relevant and of sufficient quality for further analysis.ResultsOccupational noise exposure causes between 7 and 21 % of the hearing loss among workers, lowest in the industrialized countries, where the incidence is going down, and highest in the developing countries. It is difficult to distinguish between NIHL and age-related hearing loss at an individual level. Most of the hearing loss is age related. Men lose hearing more than women do. Heredity also plays a part. Socioeconomic position, ethnicity and other factors, such as smoking, high blood pressure, diabetes, vibration and chemical substances, may also affect hearing. The use of firearms may be harmful to hearing, whereas most other sources of leisure-time noise seem to be less important. Impulse noise seems to be more deleterious to hearing than continuous noise. Occupational groups at high risk of NIHL are the military, construction workers, agriculture and others with high noise exposure.ConclusionThe prevalence of NIHL is declining in most industrialized countries, probably due to preventive measures. Hearing loss is mainly related to increasing age.Electronic supplementary materialThe online version of this article (doi:10.1007/s00420-015-1083-5) contains supplementary material, which is available to authorized users.

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Peripheral and Central Auditory Dysfunction Induced by Occupational Exposure to Organic Solvents

Cited by 45 publications

References 43 publications

Perda auditiva associada à exposição ocupacional a solventes orgânicos: uma revisão sistemática

Perda auditiva associada à exposição ocupacional a solventes orgânicos: uma revisão sistemática

Effects of combined exposure to metals, solvents, and noise on permanent threshold shifts

Occupational noise exposure and hearing: a systematic review

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