Peripheral Calcifying Odontogenic Cyst: A Case Report and Review of the Literature

Abstract

The peripheral calcifying odontogenic cyst (PCOC) accounts for less than 25% of the cases of calcifying odontogenic cysts and most commonly appears as a nodule on the gingiva. This paper aims to present both a case report of a PCOC located in the left vestibular maxilla as well as a review of the English-language literature. An 11-year-old female patient presented a swelling in the vestibular region of teeth 12 and 13. Periapical and panoramic radiographs demonstrated irregular calcification. Surgical excision was performed. Microscopic examination showed an odontogenic cystic lesion lined by ameloblastoma-like epithelium, containing numerous ghost cells. Areas of calcification associated with ghost cells could also be observed. The patient was diagnosed with PCOC. The patient has been disease-free for 36 months. The review of the cases of PCOC showed 44 well-defined cases. The mean age was of 49.4 years at the time of diagnosis. The reported cases appeared as a painless swelling, with a slight predilection for females, and were more frequently located in the anterior region of the maxilla or mandible. Surgical excision is the treatment of choice, and recurrence is rare.

Extraosseous calcifying cystic odontogenic tumor: An uncommon variant

“…[67] It is usually present as a slowly enlarging asymptomatic mass with smooth surface in the gingiva or alveolar mucosa. [9] The clinical differential diagnosis of ECCOT includes common gingival growths of non-neoplastic nature and other peripheral odontogenic tumors.…”

Peripheral calcifying cystic odontogenic tumour of the maxillary gingiva

“…Resende et al [8], in their review of 44 well-defined cases of peripheral CCOT, also found a slight predilection for females and the anterior region. However, they found a similar distribution throughout the maxillary (40.9%) and mandible (47.7%) regions.…”

Tumor odontogénico calcificante cístico associado a odontoma: relato de caso

“…Não existe predileção por sexo ou etnia. Sem diferença significativa de localização entre maxila ou mandí-bula, o TOCC apresenta-se comumente na região anterior [3][4][5] . No presente caso, a lesão desenvolveu-se em região anterior de maxila e foi diagnosticada na terceira década de vida, estando em concordância com um relevante estudo que avaliou 215 casos de TOCC intraósseo, no qual 50% dos casos associados a odontoma estavam localizados em região de incisivo a canino e 60% destes pacientes foram diagnosticados na segunda ou terceira década de vida 4 .…”

“…Em alguns casos pode provocar aumento de volume e desconforto local. O TOCC intraósseo apresenta-se como imagem radiotransparente geralmente unilocular, podendo apresentar calcificaç ões internas irregulares e associação com outros tumores odontogénicos, como o odontoma [3][4][5] .…”