Perirenal extra-adrenal myelolipoma

Hajiran, Ali; Morley, Chad; Jansen, Robert P.S.; Kandzari, Stanley J.; Bacaj, Patrick; Zaslau, Stanley; Cardinal, Jon

doi:10.12998/wjcc.v2.i7.279

Cited by 14 publications

(11 citation statements)

References 19 publications

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“…Sometimes, the imaging appearance of myelolipoma can be similar to that of liposarcoma. As a result, myelolipomas are often misdiagnosed as liposarcoma during imaging studies [6, 16]. In our case, both CT and MRI are very good identifying lesions characterized by predominant adipose tissue.…”

Section: Discussionmentioning

confidence: 78%

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Tokuyama

Takeuchi

Kuroda

et al. 2016

Case Reports in Urology

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Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements, but fewer than 50 cases have been reported in the literature. They are usually discovered incidentally during imaging studies and are often misdiagnosed as liposarcoma, which have a malignant nature, because the imaging findings of myelolipoma can be similar to those of liposarcoma. It is challenging to distinguish presacral myelolipomas from other presacral fat-containing tumors without performing a histological examination. We should consider the possibility of a malignant tumor, and imaging-guided biopsy carries a risk of tumor spread along the biopsy tract. Therefore, surgical management might sometimes be required; however, it is not necessary in all cases. We present an incidentally detected case of presacral myelolipoma that was difficult to differentiate from other malignant tumors in a 71-year-old male.

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Section: Discussionmentioning

confidence: 78%

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Tokuyama

Takeuchi

Kuroda

et al. 2016

Case Reports in Urology

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“…Differential diagnoses include other fat-containing lesions such as extramedullary hematopoiesis, angiomyolipoma, and liposarcoma [8] . Differentiation of these lesions with imaging alone can be difficult due to overlapping imaging appearances.…”

Section: Discussionmentioning

confidence: 99%

“…Biopsy is usually required to confirm the diagnosis. Histopathologic analysis reveals mature adipocytes with varying degrees of hematopoietic cell lineages including megakaryocytes, granulocytic precursors, and erythroid precursors [8] . Immunohistochemical and molecular testing has no major role currently.…”

Section: Discussionmentioning

confidence: 99%

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Multifocal extra-adrenal myelolipomas with bilateral perirenal and retroperitoneal nodal involvement—Computed tomography features

Tsui

2020

Radiology Case Reports

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Extra-adrenal myelolipomas are exceedingly rare benign tumors composed of adipose and myeloid tissues, which have been reported to occur in various sites including the retroperitoneum, pelvis, and thorax. Myelolipomas are more commonly encountered in the adrenal glands. We illustrate a case of a 72-year-old woman with surgically proven bilateral perirenal and para-aortic lymph nodal myelolipomas detected incidentally by computed tomography. Extra-adrenal myelolipomas can be difficult to distinguish from other fat-containing lesions particularly liposarcomas, which are more commonly encountered in the retroperitoneum. This case highlights the unusual multifocal involvement of extra-adrenal myelolipomas and despite its rare occurrence, should be included in the differential diagnosis of retroperitoneal lipomatous lesions.

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“…Biopsy is often required in order to make that distinction, and the presence of hematopoietic components confirms the diagnosis of extra-adrenal myelolipoma. Treatment options range from imaging follow-up-for small, asymptomatic lesions-to surgery-for symptomatic, bulky, or progressively growing lesions, as well as for cases in which the nature of the lesion remains undetermined ( 21 , 28 - 30 ) .…”

Section: Radiological Evaluation Of Retroperitoneal Massesmentioning

confidence: 99%

Practical approach to primary retroperitoneal masses in adults

2018

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Primary retroperitoneal masses constitute a heterogeneous group of uncommon lesions and represent a challenge due to overlapping imaging findings. Most are malignant lesions. Although they are more prevalent in adults, they can occur at any age. Such lesions are classified as primary when they do not originate from a specific retroperitoneal organ and are divided, according to the image findings, into two major groups: solid and cystic. The clinical findings are nonspecific and vary depending on the location of the lesion in relation to adjacent structures, as well as on its behavior. The main imaging methods used for staging and surgical planning, as well as for selecting the biopsy site and guiding the biopsy procedure, are computed tomography and magnetic resonance imaging. In most cases, the treatment is challenging, because of the size of the lesions, vascular involvement, or involvement of adjacent organs. In this article, we present a review of the retroperitoneal anatomy and a practical approach to the main imaging features to be evaluated, with a view to the differential diagnosis, which can guide the clinical management.

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Perirenal extra-adrenal myelolipoma

Cited by 14 publications

References 19 publications

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Multifocal extra-adrenal myelolipomas with bilateral perirenal and retroperitoneal nodal involvement—Computed tomography features

Practical approach to primary retroperitoneal masses in adults

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