Peritoneal Dialysis, Acute Kidney Injury, and the Saving Young Lives Program

Finkelstein, Fredric O.; Smoyer, William E.; Carter, Mary; Brusselmans, Ariane; Feehally, John

doi:10.3747/pdi.2014.00041

Cited by 28 publications

(31 citation statements)

References 11 publications

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“…Certainly, it has been well demonstrated that acute PD requires less infrastructure and training than extracorporeal therapies, but has also been shown to be more cost effective. Two studies 6,7 from India showed that acute PD costs approximately half of the cost for HD or continuous venovenous hemofiltration (CVVH), and Kilonzo et al 7 showed that it costs ~US$350 for every life saved when using manual acute PD with two hourly exchanges.…”

Section: Pd As a Viable Option For Aki In Developing Countriesmentioning

confidence: 99%

“…This project addresses one aspect of the spectrum of providing support for AKI programs and has shown that PD therapy is feasible and can be provided at a low cost with acceptable outcomes and perhaps, most importantly, that various international organizations, nongovernmental organizations, and local hospitals can collaborate to develop successful treatments for AKI. 6,7,20 …”

Section: The Saving Young Lives Programmentioning

confidence: 99%

“…6,7,27 In these settings, the advantages of PD over HD include medical and technical simplicity and the lack of need for electricity, machinery, and pure water, among other factors. 29 Importantly, excellent outcomes have been observed when using PD to treat patients with AKI.…”

Section: The Saving Young Lives Programmentioning

confidence: 99%

“…29 Importantly, excellent outcomes have been observed when using PD to treat patients with AKI. 6,7,23,27,29 Within this team effort, the international societies help provide education, training support for health care workers, and supplies. To date, successful programs have been developed at ten sites in eight countries, with three additional sites in development as of late 2015.…”

Section: The Saving Young Lives Programmentioning

confidence: 99%

“…[2][3][4][5] Second, health care resources to diagnose and manage AKI are often limited, with a lack of appropriate medications, equipment, and trained personnel. [6][7][8][9] Third, governments and other institutions such as hospitals, nongovernmental organizations, and global health initiatives have not focused sufficiently on the problems of AKI. [2][3][4][5] Finally, there is limited awareness among health care workers of the problems presented by AKI in terms of diagnosis, treatment, and management.…”

Section: Introductionmentioning

confidence: 99%

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Acute kidney injury: risk factors and management challenges in developing countries

Ponce¹,

Balbi²

2016

IJNRD

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Acute kidney injury (AKI) is a major global health problem in both developed and developing nations, negatively affecting patient morbidity and responsible for an estimated 1.4 million deaths per year. Although the International Society of Nephrology set a goal of eliminating preventable deaths from AKI by 2025, implementation of this program in developing countries presents major challenges not only because of the lack of resources but also because of the scarce data addressing the epidemiology and causes of AKI in developing countries, the limited health care resources to diagnose and treat AKI, and the poor awareness of the impact of AKI on patient outcomes.

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Section: Pd As a Viable Option For Aki In Developing Countriesmentioning

confidence: 99%

Section: The Saving Young Lives Programmentioning

confidence: 99%

Section: The Saving Young Lives Programmentioning

confidence: 99%

Section: The Saving Young Lives Programmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Acute kidney injury: risk factors and management challenges in developing countries

Ponce¹,

Balbi²

2016

IJNRD

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Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children

et al. 2022

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ImportanceIncreasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor short-term and long-term outcomes. Guidance is required to focus efforts related to expansion of pediatric AKI knowledge.ObjectiveTo develop expert-driven pediatric specific recommendations on needed AKI research, education, practice, and advocacy.Evidence ReviewAt the 26th Acute Disease Quality Initiative meeting conducted in November 2021 by 47 multiprofessional international experts in general pediatrics, nephrology, and critical care, the panel focused on 6 areas: (1) epidemiology; (2) diagnostics; (3) fluid overload; (4) kidney support therapies; (5) biology, pharmacology, and nutrition; and (6) education and advocacy. An objective scientific review and distillation of literature through September 2021 was performed of (1) epidemiology, (2) risk assessment and diagnosis, (3) fluid assessment, (4) kidney support and extracorporeal therapies, (5) pathobiology, nutrition, and pharmacology, and (6) education and advocacy. Using an established modified Delphi process based on existing data, workgroups derived consensus statements with recommendations.FindingsThe meeting developed 12 consensus statements and 29 research recommendations. Principal suggestions were to address gaps of knowledge by including data from varying socioeconomic groups, broadening definition of AKI phenotypes, adjudicating fluid balance by disease severity, integrating biopathology of child growth and development, and partnering with families and communities in AKI advocacy.Conclusions and RelevanceExisting evidence across observational study supports further efforts to increase knowledge related to AKI in childhood. Significant gaps of knowledge may be addressed by focused efforts.

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