“…A multitude of studies have addressed this issue, and various techniques and technologies have been assessed, including structured history-taking and examination [48,57,59,89,95], algorithms and scores [5,8,57,134], biochemical investigations [1,37,39], peritoneal lavage [54], computer-aided diagnosis [32], radiological investigations [20], and ultrasound [57,59,60,61,104]. Laparoscopy was initially introduced as a promising and powerful additional diagnostic tool.…”