Periungual basal cell carcinoma: A case report with review of literature

Bandyopadhyay, Debabrata; Sen, Sumit

doi:10.4103/0019-5154.80425

Cited by 3 publications

(8 citation statements)

References 32 publications

(77 reference statements)

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“…Risk factors include exposure to radiation and chemical therapies, burns, viruses, chronic trauma, azo dyes and arsenic-containing compounds [1, 2]. Arsenic exposure was reported by our patient.…”

Section: Discussion/conclusionmentioning

confidence: 71%

“…Arsenic exposure was reported by our patient. Histology reveals that these tumors usually grow slowly and originate in the epidermis and hair follicles; this means that the involvement of the nail apparatus is rare, and this can cause delays in diagnosis [1]. The clinical presentation in the periungual and subungual regions is usually variable and may be misidentified with chronic paronychia, pyogenic granuloma, squamous cell carcinoma, amelanotic melanoma, trauma, dermatophyte and bacterial infections, and eczema [4, 5].…”

Section: Discussion/conclusionmentioning

confidence: 99%

“…Dermatoscopy contributes to the diagnosis and evidence of alterations such as arboriform telangiectasia, seen in periungual BCC, and the destruction of the nail matrix, frequently found in nail tumors [2]. The average age of patients with BCC is 65 years, and the male-to-female ratio is 1.8: 1 [1]. Fingers are more affected than toes, and the thumb is the most frequently affected digit [3].…”

Section: Discussion/conclusionmentioning

confidence: 99%

“…BCC is the most common type of skin cancer and mainly affects the head and neck, but it has been described in other topographies such as the nail apparatus [1]. Risk factors include exposure to radiation and chemical therapies, burns, viruses, chronic trauma, azo dyes and arsenic-containing compounds [1, 2].…”

Section: Discussion/conclusionmentioning

confidence: 99%

“…Basal cell carcinoma (BCC) is the most common type of skin cancer [1, 2]. Nail involvement of this tumor is rare, and the pathogenesis is not entirely clear.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Subungual Basal Cell Carcinoma: A Rare Nail Tumor with a Challenging Diagnosis

Pollo

Rabay

Lima

et al. 2019

Skin Appendage Disord

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Subungual basal cell carcinoma (BCC) is a rare disorder associated with many factors, including contact with some topical and oral substances. A differential diagnosis and an early approach are important to minimize the functional damage of the limbs affected by this type of tumor. We report a case of subungual BCC in a 70-year-old woman that was managed by surgical excision. The patient’s medical history included the previous use of arsenic. We emphasize the contribution of an early diagnosis to achieve better treatment results in this instance.

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Section: Discussion/conclusionmentioning

confidence: 71%

Section: Discussion/conclusionmentioning

confidence: 99%

Section: Discussion/conclusionmentioning

confidence: 99%

Section: Discussion/conclusionmentioning

confidence: 99%

“…Basal cell carcinoma (BCC) is the most common type of skin cancer [1, 2]. Nail involvement of this tumor is rare, and the pathogenesis is not entirely clear.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Subungual Basal Cell Carcinoma: A Rare Nail Tumor with a Challenging Diagnosis

Pollo

Rabay

Lima

et al. 2019

Skin Appendage Disord

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Periungual basal cell carcinoma

Tavares¹,

Costa²,

Delcourt³

et al. 2018

An. Bras. Dermatol.

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Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit can shorten the diagnostic process and avoid destructive treatment and functional damage.

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Clinical and Dermoscopic Patterns of Basal Cell Carcinoma and Its Mimickers in Skin of Color: A Practical Summary

Karampinis,

Georgopoulou,

Kampra

et al. 2024

Medicina

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The diagnosis of basal cell carcinoma (BCC) in dark phototypes can be a challenging task due to the lack of relevant clues and its variable presentation. In this regard, there is growing evidence that dermoscopy may benefit the recognition of BCC even for skin of color (SoC). The objective of this review is to provide an up-to-date overview on clinical and dermoscopic patterns of BCC in SoC, also comparing such findings with those of the main clinical mimickers reported in the literature. A comprehensive search of the literature through the PubMed electronic database was carried out in order to identify papers describing the clinical and dermoscopic features of BCC in dark phototypes (IV–VI). By finding macroscopic clinical presentations of BCCs in SoC patients and any possible clinical mimickers considered in the retrieved papers, we built a differential diagnosis list and analyzed the dermoscopic findings of such conditions to facilitate the diagnosis of BCC. BCC in darker skin may present as pigmented nodular lesions, pigmented patches or plaques, ulcers, erythematous nodular lesions, erythematous plaques or patches, or scar-like lesions, depending on its subtype and body site. The differential diagnosis for BCC in patients with SoC includes squamous cell carcinoma, melanoma, nevi, adnexal tumors and sebaceous keratosis. Additionally, it differs from that of Caucasians, as it also includes lesions less common in fair skin, such as dermatosis papulosa nigra, melanotrichoblastoma, and pigmented dermatofibrosarcoma protuberans, and excludes conditions like actinic keratosis and keratoacanthoma, which rarely appear in darker skin. The resulting differences also include infectious diseases such as deep cutaneous mycosis and inflammatory dermatoses. The most prevalent differentiating dermoscopic feature for BCC includes blue, black and gray dots, though arborizing vessels still remain the predominant BCC feature, even in dark phototypes. Diagnostic approach to BCC in dark-skinned patients varies due to the prevalence of dermoscopy findings associated with hyperpigmented structures. Clinicians should be aware of such points of differentiation for a proper management of this tumor in SoC.

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Periungual basal cell carcinoma: A case report with review of literature

Cited by 3 publications

References 32 publications

Subungual Basal Cell Carcinoma: A Rare Nail Tumor with a Challenging Diagnosis

Subungual Basal Cell Carcinoma: A Rare Nail Tumor with a Challenging Diagnosis

Periungual basal cell carcinoma

Clinical and Dermoscopic Patterns of Basal Cell Carcinoma and Its Mimickers in Skin of Color: A Practical Summary

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