The present research brings an input of information regarding the evolution of several physico-chemical parameters of two salt lakes (Lake Ocnei and Lake Rotund), part of the ”Salina Turda” resort, Cluj County, Romania, by means of on-site determinations. Measurements were carried out at six depths for each sampling point. We attempted to describe the behaviors of the two lakes under different natural conditions, in order to identify the impact of anthropogenic activities on the quality parameters of the two lakes. Our studies showed that the qualitative parameters of the water fluctuate as an effect of anthropogenic activities. A comparative analysis of the results gathered during three monitoring campaigns in 2016, 2018, and 2020 indicated that water quality was affected by anthropogenic activities such as mixing water layers which were characterized by different salinity values. The lakes tended to lose basicity, pH values varying between 9 at the surface level and 7 at −4 m. The thermal stratification phenomenon was only evident in the first year of monitoring; later on, the waters of both lakes appeared thermally homogenous down to the depth of −2 m. It was determined that the lakes had an uppermost freshwater layer, which disappeared during the bathing season because of vertical mixing. Interestingly, the two lakes showcased different behaviors at depths beyond −3 m. In addition, the infiltration of meteoric water that was polluted with nitrites and nitrates demonstrated the fact that anthropogenic activities that take place in the vicinity of the lakes generate negative effects on water quality. The presence of the heliothermal phenomenon was confirmed by the measurements made in the upper segment of the lakes. This layer of water consists of a mixture of fresh and salt water. The purpose of the research was to evaluate the water quality of the lakes, monitor its evolution during the bathing season and update the situation regarding the water quality of the two salt lakes by testing specific parameters.