This study examines durability and mechanical properties of sustainable self-consolidating concrete (SCC) in which 80% of the cement is replaced with combinations of recycled industrial by-products including fly ash, silica fume, and ground granulated blast furnace slag (GGBS). The water to binder (w/b) ratio of SCC mixes studies was maintained at 0.36. The study proposes empirical relationships to predict 28-day compressive strengths based on the results of three-day and seven-day compressive strengths. In addition, the chloride penetration resistance of the various sustainable SCC mixes was determined after three days, seven days, and 28 days of moist curing of concrete standards. It was concluded that fly ash, silica fume, and GGBS contribute favorably to enhancing strength development, fresh properties, and durability of SCC in comparison to ordinary Portland cement (OPC). The compressive strength of the sustainable SCC mixes falls within ranges suitable for structural engineering applications. Replacing cement with 15% silica fume produced a 28-day average compressive strength of 95.3 MPa, which is 44.2% higher than the control mix. Replacing cement with 15% or 20% silica fume reduced the chloride ion permeability to very low amounts compared to high permeability in a control mix. replacement of cement in SCC mixes results in loss of concrete compressive strength during the early stages, but, in many cases, a significant increase in compressive strength develops during later stages.Adding 3.8% silica fume improves compressive strength, splitting, tensile strength, and durability of SCC mixes Quercia [5]. It was found that replacing 15% of cement by silica fume resulted in a 28-day compressive strength of 95.3 MPa, which was 44% higher than the control SCC mix examined in the study by Mohamed and Najm [6]. Due to their spherical morphology, which reduces inter-particle friction, both silica fume and fly ash enhance workability and is essential for producing high strength concrete.Partial replacement of cement in SCC with various industrial byproduct wastes such as limestone power, cement kiln dust, and pulverized steel slag improves resistance to chloride penetration [7]. Other studies, however, contend that, under laboratory conditions, the durability of SCC and traditional vibrated concrete may be comparable [8] and that using Rapid Chloride Penetration Test (RCPT) to assess durability of SCC does not produce reliable results. However, the same study acknowledges that the quality of compacting vibrated concrete onsite is unlikely to reach the quality of SCC. As a result, concrete structures built with SCC may still be more durable.Partial replacement of cement with GGBS in SCC enhances compressive strength and durability. In one study, it was shown that replacing 70% of cement in a particular SCC mix resulted in strength as high as the control SCC mix [9].Alkali-silica reaction (ASR) may lead to significant long-term damage and degradation of concrete properties [10]. GGBS is known to improve concrete resis...