Persistence of triamcinolone acetonide following macular hole surgery

Yamauchi, Yukihide; Nakamura, Hisahide; Hayakawa, Kazuhisa; Sawaguchi, Shoichi

doi:10.1111/j.1600-0420.2006.00702.x

Cited by 15 publications

(10 citation statements)

References 4 publications

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“…Fukukita et al 34 reported a case where TA was noted postoperatively on the surface of the residual SF 6 gas bubble, but this did not interfere with hole closure and vision improved from 20/250 preoperatively to 20/25 postoperatively. Yamauchi et al 35 described two cases where TA was used for vitrectomy and ILM peel and although there was a period of time of persistence of TA in the postoperative period, anatomic closure was also achieved in both cases and visual acuity improved. Fortunately, there were no intraoperative or postoperative complications attributed to the use of TA in our study.…”

Section: Discussionmentioning

confidence: 94%

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Macular Hole Closure With Triamcinolone-Assisted Internal Limiting Membrane Peeling

Tewari¹,

Almony²,

Shah³

2008

Retina

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Section: Discussionmentioning

confidence: 94%

“…32,33 There have been anecdotal case reports that have described persistence of TA in the macular hole after vitrectomy surgery but no long-term study has evaluated final outcomes. 34,35 In this article, we report the anatomic and visual outcomes of macular hole surgery with triamcinoloneassisted ILM peeling.…”

mentioning

confidence: 98%

Macular Hole Closure With Triamcinolone-Assisted Internal Limiting Membrane Peeling

Tewari¹,

Almony²,

Shah³

2008

Retina

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“…The deposition of residual TA crystal on fovea after MHS has not been associated with poor visual outcome or interference with the closure of hole. [78]…”

Section: Discussionmentioning

confidence: 99%

Residual triamcinolone acetonide at macular hole after vitreous surgery

Kumar

Sinha

Gupta

2010

Indian J Ophthalmol

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Post traumatic macular holes have shown successful anatomic outcomes with vitrectomy with internal limiting membrane (ILM) peeling and gas injection. Intraocular use of triamcinolone acetonide (TA) crystals is gaining popularity in patients for visualization of the vitreous cortex, posterior vitreous detachment induction and ILM peeling during macular hole surgery. However, the possibility of residual steroid crystals clogging the hole at the conclusion of surgery exists. In our case, residual TA was observed biomicroscopically in the fovea on the seventh day after surgery, Optical Coherence Tomography (OCT) image of the eye showed a hyper reflective mass corresponding to the TA. However, a repeat OCT carried out four weeks after surgery showed recovery of the foveal morphologic features to an almost normal depression, with closure of the hole. Residual TA crystals in the macular hole post vitreous surgery may not interfere with ultimate macular hole closure or visual improvement.

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“…However, additional studies are necessary to validate this hypothesis [21]. Although intraoperative use of triamcinolone and its presence during the follow-up period may be related to delayed closure and reopening of MHs [22,23] those did not occur in our group of patients.…”

Section: Discussionmentioning

confidence: 67%

Surgical Management of Macular Hole at 2 Years of Follow-Up

Badaró¹,

Navarro²,

Lima-Sousa³

et al. 2015

J Clin Exp Ophthalmol

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Purpose: To determine prognostic factors, anatomic success rate and safety of sutureless pars plana vitrectomy and vitreous base removal associated to internal limiting membrane (ILM) peeling, C3F8 injection and 1-day facedown postoperative positioning to manage idiopathic macular holes (MHs) at 2 years follow-up.Methods: Forty-six eyes with an idiopathic MH underwent pars plana vitrectomy, ILM peeling after Brilliant Blue 0.05 mg/ml staining, and gas tamponade. Patients remained facedown for 1 day postoperatively. Follow-up included measurement of best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) at 1 and 7 days and 1, 6, 12, and 24 months postoperatively. If the MHs were not anatomically closed by 1 month, another procedure was performed.Results: Primary and final anatomical closure rate were 91.3% and 97.8%, respectively. Mean BCVA improvement (logarithm of the minimum angle of resolution, LogMAR) was 0.34. No late MH reopening occurred, no surgery-related or ocular dye-related complications developed. The BCVA was less likely to improve in MHs with longer symptomatic periods or larger internal diameters. Conclusion:Pars plana vitrectomy combined with vitreous base removal and ILM peeling using Brilliant Blue 0.05% associated to C3F8 injection and 1-day facedown postoperative positioning for idiopathic MHs is a safe surgical approach, achieving a MH closure rate of 91.3% after one procedure and 97.8% after a second one. Long symptoms duration and larger inner MH diameter are associated with poor BCVA.Keywords: Chromovitrectomy; Brilliant Blue; Macular hole; Vital dyes; Vitrectomy Summary StatementSutureless pars plana vitrectomy associated to posterior hyaloid detachment, internal limiting membrane peeling guided by brilliant blue, staining vitreous base removal, C3F8 injection and 1-day facedown postoperative positioning is a safe and effective surgical technique for management of macular holes.

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Persistence of triamcinolone acetonide following macular hole surgery

Cited by 15 publications

References 4 publications

Macular Hole Closure With Triamcinolone-Assisted Internal Limiting Membrane Peeling

Macular Hole Closure With Triamcinolone-Assisted Internal Limiting Membrane Peeling

Residual triamcinolone acetonide at macular hole after vitreous surgery

Surgical Management of Macular Hole at 2 Years of Follow-Up

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