2010
DOI: 10.3109/1547691x.2010.489528
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Persistent infections and their relationship with selected oncologic and non-tumor pathologies

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Cited by 4 publications
(4 citation statements)
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“…The associations of CLL with bacterial [28] and viral infections (hepatitis C virus, cytomegalovirus -CMV) [37][38][39][40][41] have been discussed. On the other hand, we previously showed that clean-up workers of Chornobyl Nuclear Power Plant accident had a significantly greater incidence of CMV infection and hepatitis C virus seropositivity as compared with the control group of IR-non-exposed persons [14].…”
Section: Discussionmentioning
confidence: 83%
See 1 more Smart Citation
“…The associations of CLL with bacterial [28] and viral infections (hepatitis C virus, cytomegalovirus -CMV) [37][38][39][40][41] have been discussed. On the other hand, we previously showed that clean-up workers of Chornobyl Nuclear Power Plant accident had a significantly greater incidence of CMV infection and hepatitis C virus seropositivity as compared with the control group of IR-non-exposed persons [14].…”
Section: Discussionmentioning
confidence: 83%
“…It is known that in addition to the tumorigenic effect, ionizing radiation (IR) increases the risk of somatic and immune system disorders, persistent viral infections [10][11][12][13][14]. We assume that the indirect effect of IR (through imbalance of the immune system, the appearance of excess autoantigens, viral and microbial antigens) could influence the selection of B-cell clones for subsequent transformation into CLL.…”
Section: Doi: 1032471/exp-oncology2312-8852vol-42-no-314839mentioning
confidence: 99%
“…Regardless of whether HBV or HCV contributes to the development of chronic lymphocytic leukemia, it remains conceivable that either virus could alter the natural history or aggressiveness of the malignancy (29). Here again, we were unable to find reason for concern in that Rai staging and the distribution of established markers for chronic lymphocytic leukemia aggressiveness, such as IgV H mutational status, β 2 -microglobulin levels, Zap-70 and CD38 status, were similar in chronic lymphocytic leukemia patients with and without evidence of HBV or HCV infection (30).…”
Section: Discussionmentioning
confidence: 99%
“…In humans, HTLV-1 causes T-cell lymphoma, and Epstein-Barr virus (EBV) may be involved in the development of Burkitt lymphoma (2). For CLL, many viral associations have been suggested, including HTLV-1 (12), EBV (13), HPV (14), Merkel cell polyomavirus (MCPyV) (15), hepatitis C virus and cytomegalovirus (16), but no definitive causation has been shown. Although there are no known human Bcell leukemia viruses, both bovine leukemia virus and feline leukemia virus cause a B-cell leukemia in appropriate animals with features similar to those of human CLL (17,18).…”
Section: Introductionmentioning
confidence: 99%