“…However, research on population-wide interventions is lacking. The vast majority of tested interventions have been individual-, hospital-, health plan -, or community-directed approaches involving strategies to address personal, systems, and/or cultural barriers to screening (9,(15)(16)(17)(18)(19)(20)(21). These interventions are unsuitable for population-wide implementation because of their complexity, high cost, relatively small reach, and limited generalizability.…”