Perspective: The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partner Scientific Board (PPSB)

Abstract

The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partner Scientific Board (PPSB) is comprised of representatives of private, for-profit entities (including pharmaceutical, biotechnology, diagnostics, imaging companies, and imaging contract research organizations), and nonprofit organizations that provide financial and scientific support to ADNI through the Foundation for the National Institutes of Health. The PPSB serves as an independent, open, and precompetitive forum in which all private sector and not-for-profit partners in ADNI can collaborate, share information, and offer scientific and private-sector perspectives and expertise on issues relating to the ADNI project. In this article, we review and highlight the role, activities, and contributions of the PPSB within the ADNI project, and provide a perspective on remaining unmet needs and future directions.

The Worldwide Alzheimer's Disease Neuroimaging Initiative: An update

“…The PPSB established several scientific workgroups to address needs and gaps in the field. More detail on the PPSB and its role in ADNI-2 can be found in this issue of Alzheimer's & Dementia [86].…”

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

“…ADNI is structured as a public-private partnership overseen by the Private Partner Scientific Board comprising representatives of private, for-profit entities, and nonprofit organizations which facilitates precompetitive collaboration [3]. ADNI has been described as an exemplar of how these partnerships can impact both clinical and basic science research [4].…”

Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

“…Appendix e-1 and table e-1 at Neurology.org, http://www. adni-info.org, http://adni.loni.usc.edu, and previous reports [7][8][9][10][11][12][13][14][15][16][17][18][19][20] give more information.…”