2010
DOI: 10.1002/med.20233
|View full text |Cite
|
Sign up to set email alerts
|

Perspectives and potential applications of nanomedicine in breast and prostate cancer

Abstract: Nanomedicine is a branch of nanotechnology that includes the development of nanostructures and nanoanalytical systems for various medical applications. Among these applications, utilization of nanotechnology in oncology has captivated the attention of many research endeavors in recent years. The rapid development of nano-oncology raises new possibilities in cancer diagnosis and treatment. It also holds great promise for realization of point-of-care, theranostics, and personalized medicine. In this article, we … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
38
0

Year Published

2011
2011
2024
2024

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 44 publications
(38 citation statements)
references
References 217 publications
(383 reference statements)
0
38
0
Order By: Relevance
“…Representative examples of NIR fluorescent dyes include indocyanine green, an FDA-approved NIR dye20, 21, and cypate, a readily functionalized indocyanine green analog 22. We demonstrate that the device can detect fluorescence from as low as 1 nM of indocyanine green dye (Fig.…”
Section: Resultsmentioning
confidence: 85%
“…Representative examples of NIR fluorescent dyes include indocyanine green, an FDA-approved NIR dye20, 21, and cypate, a readily functionalized indocyanine green analog 22. We demonstrate that the device can detect fluorescence from as low as 1 nM of indocyanine green dye (Fig.…”
Section: Resultsmentioning
confidence: 85%
“…Interestingly, nanocarriers can passively accumulate in the leaky vasculature, typical of tumor tissues in a manner known as the enhanced permeability and retention effect (EPR) [100]. Nanocarriers may also be conjugated with specific ligands, to utilize active targeting mechanisms [101]. This allows them to reach specific tissues and release drugs in a stable and controlled manner.…”
Section: Nanomaterials As Therapeutic Toolsmentioning
confidence: 99%
“…The creation of an “industrial culture” of making nanomedicines including their standardized testing and characterization is another challenge. It appears that nanomedicines currently under development will target the most common cancers, such as breast and prostate cancer [55]. The first generation of anti-cancer nanomedicines is based on their “passive” (EPR-mediated) delivery into tumors, and drugs (such as Doxil®) and diagnostic agents (such as SPION (superparamagnetic iron oxide nanoparticles)-based NMR contrast agents) are now approved and in active clinical trials, respectively [56].…”
Section: Pharmacologic Characterization and Propertiesmentioning
confidence: 99%