The cost-eectiveness of resistive plate chamber detectors and their very good timing characteristics, open the possibility to build aordable time-of-ight positron emission tomography systems with a large axial eld-of-view. Simulations suggest that, under reasonable assumptions, the absolute 3D true sensitivity, spatial resolution, and noise equivalent count rate of such systems for human whole-body screening, may exceed that of present crystalbased PET technology. However, due to the lack of energy resolution, although having energy sensitivity, the scatter fraction is expected to be considerably higher than that presented by crystal-based PET scanners. In the present paper, the simulation work done so far to access the expected performance of a resistive plate chamber time-of-ight-PET system with 2400 mm length axial eld-of-view, a time resolution of 300 ps full width at half maximum for photons pairs, and depth-of-interaction information, will be revised.