Background:
Iron deficiency and iron-related disorders are common health issues
worldwide, affecting a significant proportion of the population. Diagnosis and management
of these disorders rely heavily on using various iron-related biomarkers that
can provide valuable clinical information.
Objective:
This review article provides an overview of the most commonly used iron-related
biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor,
zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers,
such as hepcidin and retinol-binding protein 4, are also discussed.
Results:
Iron plays a vital role in various physiological processes, including oxygen transport,
energy metabolism, and DNA synthesis. The article highlights the advantages and
limitations of iron biomarkers and their clinical applications in diagnosing and managing
iron deficiency and iron-related anemia.
Conclusion:
Using iron-related biomarkers in screening and monitoring programs can
improve patient outcomes and reduce healthcare costs.