Pes14 Medication and Health Care Service Utilization Related to Depressive Symptoms in Older Adults With Psoriasis

Kulkarni, A; Balkrishnan, R; Camacho, F; Anderson, RT; Feldman, SR

doi:10.1016/s1098-3015(10)62194-8

Cited by 21 publications

(38 citation statements)

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“…Indeed, patients with depression are less compliant with the use of antipsoriatic medication and use health care service less frequently. [42][43][44] High rate of noncompliance with therapy among depressed individuals is also a well-known problem in other fields of medicine, for example, in diabetology and cardiology. 45,46 In a potentially vicious cycle, noncompliance can result in deteriorated treatment outcome, which might trigger or worsen depression.…”

Section: Discussionmentioning

confidence: 99%

Comorbidities significantly impact patients’ preferences for psoriasis treatments

Schmieder

Schaarschmidt

Umar

et al. 2012

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

Comorbidities significantly impact patients’ preferences for psoriasis treatments

Schmieder

Schaarschmidt

Umar

et al. 2012

Journal of the American Academy of Dermatology

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“…Older patients with a higher incidence of depression according to the CES-D scale comply poorly with topical therapy and are also less likely to utilize healthcare resources than younger patients. 21 The negative effect of psoriasis on patient quality of life has been quantifi ed. A survey conducted by the National Psoriasis Foundation revealed that 79% of patients with severe disease believed that psoriasis had a negative effect on their lives.…”

Section: Psoriasis and The Risk Of Depressionmentioning

confidence: 99%

Depression and Quality of Life in Psoriasis

Voorhees

Fried

2009

Postgraduate Medicine

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Psoriasis is a chronic inflammatory hyperproliferative disease of the skin, scalp, nails, and joints. The physical symptoms of psoriasis include itching, irritation, burning/stinging, sensitivity, and pain. Patients also suffer psychological distress, especially as a result of stigmatization, self-consciousness, and embarrassment, which can in turn affect employment and social activities. Relatively high rates of depression are reported in patients with psoriasis. Inflammatory cytokines such as tumor necrosis factor alpha, interferon gamma, and other type 1 cytokines play an important role in the pathogenesis and comorbidities of psoriasis. Data from both animal and human studies suggest that these cytokines are linked to depression. Some psoriasis treatments have demonstrated improvements in symptoms of psoriasis as well as in measures of depression and health-related quality of life. Physicians managing patients with psoriasis must be aware of the psychological effects of psoriasis and need to use a multifaceted approach to managing this disease, focusing on both the physical and psychological aspects.

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“…Psychiatric comorbidity is a strong predictor of poor adherence [6,7]. Depression in psoriasis patients may reduce adherence to treatment, resulting in worse psoriasis and more depression [7].…”

Section: Introductionmentioning

confidence: 99%