PET-CT Demonstration of Extensive Muscle Metastases From Breast Cancer

Detection of skeletal muscle metastasis: torso FDG PET-CT versus contrast-enhanced chest or abdomen CT

“…Skeletal muscles are usually at the periphery of the FOV of chest or abdomen CT scans, and are apt to receive less attention. Recently SMM from various malignancies have been reported in several case reports and a few clinical studies of PET-CT due to its almost complete covering of the whole body and higher sensitivity (6,(10)(11)(12)(13)(14).…”

“…The reported prevalence of skeletal muscle metastasis (SMM) among cancer patients varies, in the range of 0.03-17.5%, with a relatively higher prevalence of [6][7][8][9][10][11][12][13][14][15][16][17].5% in autopsy studies (2,3) compared to 0.03-5.6% in clinical imaging-based studies (4)(5)(6), indicating that more sensitive imaging modalities are required to detect SMM (7).…”

Muscle metastasis of carcinoma

“…There are many articles in which positron emission tomography (PET) has demonstrated extensive skeletal muscle metastasis from diverse neoplasias, such as breast cancer [27] or carcinoma of the oesophagus [28]. Nowadays, there is a growing body of literature regarding the added value of F-18 FDG PET/CT in cancer patient management [29].…”

Malignant amelanotic melanoma - A diagnostic surprise: Flurodeoxyglocose positron emission tomography-Computed tomography and immunohistochemistry clinch the ′final diagnosis′

“…[8] Other malignancies that are reported to have solitary distant muscle metastases include the breast, esophagus, lung, and kidney cancers; however, descriptions of extensive muscular metastases are exceedingly rare. [9] FDG PET/CT is considered as a sensitive tool in detecting intramuscular metastases. A recently performed review of one series and 33 case reports of 'detection of muscle metastases on FDG PET/CT' found this modality to impact management in as many as 51% of the cases of malignancies.…”