Peutz-Jeghers Colonic Tumour in a Newborn

Abstract

The authors refer a case report of the Peutz-Jeghers tumour localised in transverse colon found during a systematic clinical examination of the 4-day-old newborn, without any signs of intestinal occlusion. The end-to-end colic resection was made. Post-operative course was without any complications. The observation is rarely due to the tumour's atypical localisation as well as its presence in the newborn.

Follow‐up and Surgical Management of Peutz‐Jeghers Syndrome in Children

“…In the intestinal tract, early polyposis leads to clinical signs. One-third of the time its first manifestations occur during the first decade of life, 50% of the time before the patient is 20 years old, and sometimes it occurs in the neonatal period (3,5,6). This hamartomatous polyposis is located in the small bowel in 90% of patients, most often in the jejunum, followed by the ileum and duodenum (2).…”

Small Bowel Intussusception in a 16-Month-Old Child With Peutz-Jeghers Syndrome

“…9-11 The earliest was at 4 days of life, when an asymptomatic neonate had a large abdominal mass palpated on routine examination and was found to have a large colonic tumor and multiple other small colonic polyps. 10 A 9-day-old had gastric outlet obstruction caused by 3 Peutz-Jeghers polyps. 9 Another neonate at 15 days of life was found to have an ileocecal intussusception requiring surgical resection; this patient is the youngest reported patient with PJS to have intussusception.…”

“…There are only 4 case reports in the literature describing patients diagnosed with PJS who are younger than 6 months of age. [9][10][11][12] Three of these reports describe neonates with PJS. [9][10][11] The earliest was at 4 days of life, when an asymptomatic neonate had a large abdominal mass palpated on routine examination and was found to have a large colonic tumor and multiple other small colonic polyps.…”

“…On review of the literature, [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] our patient is a rare case. He was diagnosed with PJS at the early age of 6 months and subsequently developed the complication of small bowel intussusception at the age of 16 months.…”

Peutz-Jeghers Syndrome Causing Gastroduodenal Intussusception : A Rare Case Report

“…1 Exact etiology of this disorder is unknown but mutation in gene STK11 is found to be one reason. 2 Most common age of presentation is usually 30 to 40 years, but in about 33% of cases, they can be diagnosed before ten years. Usually, they present with intestinal intussusception or intestinal bleeding, and gastroduodenal intussusception is an infrequent presentation.…”