pH sensing using whispering gallery modes of a silica hollow bottle resonator

Stoian, Razvan-Ionut; Lavine, Barry K.; Rosenberger, A. T.

doi:10.1016/j.talanta.2018.10.077

Cited by 26 publications

(16 citation statements)

References 34 publications

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“…developed an optical pH sensor, which can deposit swellable pH‐sensitive polymer particles on the inner surface of the microbottle resonators and monitor the titration curve to determine the changes of pH and RI of particles. The optimal resolution of the device is 0.06 pH units and the response time is 10–15 s . This method provided constructive results for realizing the surface functionalization of resonators in the future.…”

Section: Structure and Application Of Wgmrsmentioning

confidence: 94%

“…With the continuous improvement of WGMRs in optical sensing, many novel geometric structures have appeared in recent years, such as: microdisk, [17,[116][117][118][119][120][121][122][123][124][125] microbubble, [126][127][128][129][130][131][132] microbottle, [133][134][135][136][137][138][139][140][141][142][143][144][145][146][147] microtube, [148][149][150][151][152][153][154][155][156][157][158][159][160] microcylinder, [161][162][163] etc. These new resonators are widely used in the field of phy...…”

Section: Preparation and Application Of Other Types Of Resonatorsmentioning

confidence: 99%

“…With the continuous improvement of WGMRs in optical sensing, many novel geometric structures have appeared in recent years, such as: microdisk, microbubble, microbottle, microtube, microcylinder, etc. These new resonators are widely used in the field of physical biochemistry.…”

Section: Structure and Application Of Wgmrsmentioning

confidence: 99%

See 2 more Smart Citations

Whispering Gallery Mode Optical Microresonators: Structures and Sensing Applications

Cai

Pan

Zhao

et al. 2020

Physica Status Solidi (a)

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Whispering gallery mode resonators (WGMRs) have achieved significant results due to their unique properties such as extremely small mode volume, ultra‐high quality (Q) factor, fast dynamic response, and ultra‐high sensitivity. WGM is commonly used in theoretical physics research, nonlinear optics, optoelectronic devices, and the preparation of high‐sensitivity sensors. This article briefly introduces the basic characteristics and sensing principle of WGM, the manufacturing method of WGMRs, and the sensing applications of microresonators in the fields of physics, chemistry, and biology. The detection limits of physical parameters and the detection sensitivity of biomolecules in recent decades are summarized. In addition, the advantages and disadvantages of different structures and the development trend of WGMRs applications are discussed.

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Section: Structure and Application Of Wgmrsmentioning

confidence: 94%

Section: Preparation and Application Of Other Types Of Resonatorsmentioning

confidence: 99%

See 1 more Smart Citation

Whispering Gallery Mode Optical Microresonators: Structures and Sensing Applications

Cai

Pan

Zhao

et al. 2020

Physica Status Solidi (a)

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“…For example, poly(N-isopropylacrylamide) (polyNIPA), poly(acrylic acid) (PAA) and poly (allylamine hydrochloride) hydrogels have sensitive pH-response characteristics. [78,117] Calcium alginate hydrogel, hydroxypropyl methylcellulose hydrogel, and polyvinyl alcohol (PVA) hydrogel can be used as humidity sensitive materials for optical fiber humidity sensors. [118][119][120][121] On the other hand, they can be used as matrix to encapsulate or immobilize specific chemicals, luminescent materials or biological receptors for biochemical detection.…”

Section: Polymersmentioning

confidence: 99%

mentioning

confidence: 99%

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Zhang

Zhou

et al. 2021

Laser & Photonics Reviews

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Optofluidic, as an emerging technology that combines photons and microfluidics, has become a powerful, intelligent, and universal sensing platform in the field of bio-chemical sensing. Optical fiber optofluidic (OFOF), as a branch of optofluidic technology, has stimulated a host of remarkable achievements in the field of bio-chemical sensing due to its superiority of compact structure, immunity to electromagnetic interference, low sample consumption, high sensitivity, and real-time dynamic response. In this paper, an overview of OFOF bio-chemical sensors is presented. The OFOF system architectures are introduced and some advanced functional materials and coating technologies that can be utilized in the OFOF sensing platform to achieve high-performance biochemical sensing are summarized. Research progress and current status of OFOF bio-chemical sensors based on various sensing mechanisms are summarized and analyzed, with emphases on their sensing principles, sensing structures, sensing applications, advantages, and disadvantages. Lastly, the existing challenges and future development trends of OFOF biochemical sensors are briefly discussed.

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Plasmon‐Coupled GaN Microcavity for WGM Lasing and Label‐Free SERS Sensing of Biofluids

Sun,

Mao,

Xia

et al. 2023

Advanced Optical Materials

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A signal amplification strategy is always required to improve sensing performance, especially for mass‐prepared, miniature and highly sensitive testing equipment. Herein, an on‐chip integrated biosensor combining microcavity lasing and surface enhanced Raman scattering (SERS) for label‐free biochemical analysis is developed. The gallium nitride (GaN) microrings array is fabricated as a whispering gallery mode microlaser based on totally internal wall reflection, and gold nanoparticles (AuNPs) are further assembled on the cavity surface to confine the optical field synergistically. The improvement of lasing capability indicates the strong light‐matter interaction that is conducive to superior response of biomolecules. As a functional example, a GaN/AuNPs substrate is employed in a urine assay, which avoids the shortcomings of requiring specific reactive reagents on different display modules. Ultimately, the chip not only realizes a wide range of pH (3.6–7.8) identification depending on the ultra‐sensitivity feedback of lasing to the refractive index of liquids, but also significantly enhances SERS signals to enable real‐time determination of the biomolecules in human urine. Even the lowest levels of creatinine (0.02%) can be quantitatively detected in less than a minute; thus this work with dual‐mode spectral analyses realizes rapid diagnosis for urinary systems, as well as provides a more accurate reference for the screening of other diseases.

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pH sensing using whispering gallery modes of a silica hollow bottle resonator

Cited by 26 publications

References 34 publications

Whispering Gallery Mode Optical Microresonators: Structures and Sensing Applications

Whispering Gallery Mode Optical Microresonators: Structures and Sensing Applications

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Plasmon‐Coupled GaN Microcavity for WGM Lasing and Label‐Free SERS Sensing of Biofluids

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