Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China

Peng, Qunjia; Song, Jinming; Li, Xuegang; Yuan, Huamao; Liu, Mengtan; Duan, Liqin; Zuo, Jiane

doi:10.1016/j.envpol.2020.115245

Cited by 19 publications

(5 citation statements)

References 53 publications

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“…Thus, the tetracycline was selected, due to its potential to reach soil and the aquatic environment [38][39][40][41][42]. Tetracycline residues were commonly detected on the soil [43][44][45][46], sediments [47][48][49][50], surface water [51][52][53], in the groundwater [54][55][56][57], wastewater [58][59][60][61][62][63].…”

Section: Introductionmentioning

confidence: 99%

Tetracycline Removal from Water by Adsorption on Geomaterial, Activated Carbon and Clay Adsorbents

Hamoudi

Hamdi

Brendlé

2021

Ecological Chemistry and Engineering S

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The use of antibiotics for breeding and for humans increased considerably in recent years, as a dietary supplement to enhance animal growth. This frequent use leads to the detection of residues in water and wastewater. Thus, the emergence of new strains of bacteria resistant to these antibiotics and, can lead to incurable diseases of livestock, and can lead to a possible transmission of these strains to humans. The purpose of this work is to develop new materials based on treated Maghnia clay, activated carbon, cement, and PVA polymer, named geomaterials. These materials were intended for the containment of hazardous wastes in landfills. The removal of tetracycline from aqueous solution was tested by adsorption onto synthesised geomaterials and their mineral constituents. Adsorption kinetics revealed that tetracycline was rapidly retained by GM and ATMa. This was confirmed by the relatively short equilibrium time of 30 min. The pseudo-second-order and intraparticle models well fitted the adsorption kinetic of the TC-adsorbent studied systems. It was noticed that the adsorption kinetic passes through several mechanisms, was demonstrated by the multi-linearity on the plot of qt against the square root of t. The adsorption capacity (Qa ) of TC onto GM is pH-dependent. Indeed, Qa reaches a maximum value (Qa = 12.58 mg ∙ g–1 at a very acidic pH of 2, then the adsorbed amount decreases to reach a minimum value at pH of 8, and for basic pHsQa increases up to 10 mg ∙ g–1.

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Section: Introductionmentioning

confidence: 99%

Tetracycline Removal from Water by Adsorption on Geomaterial, Activated Carbon and Clay Adsorbents

Hamoudi

Hamdi

Brendlé

2021

Ecological Chemistry and Engineering S

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“…Pharmaceutically active compounds (PhACs) are an important class of emerging contaminants, including nonsteroidal anti-inflammatory drugs, antibiotics, etc., widely used in medical, animal husbandry, and biotechnology fields. , PhACs are consumed in large quantities and vary in molecular structure. In comparison to traditional pollutants, their particular pharmacological and physiological properties make them more biologically active, persistent, and bioaccumulative, thus posing severe threats to ecosystems. − Diclofenac (DCF) is a nonsteroidal anti-inflammatory medication extracted from phenylacetic acid. It is often used for anti-inflammatory, pain relief, and antipyretics.…”

Section: Introductionmentioning

confidence: 99%

Semirational Design Strategy To Enhance the Thermostability and Catalytic Activity of Cytochrome P450 105D7 for the Degradation of the Pharmaceutically Active Compounds: Diclofenac

Zhu,

Xu,

Zhang

et al. 2024

Environ. Sci. Technol.

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Pharmaceutically active compounds are an important category of emerging pollutants, and their biological transformation processes in the environment are crucial for understanding and evaluating the migration, transformation, and environmental fate of emerging pollutants. The cytochrome P450 105 enzyme family has been proven to play an important role in the degradation of exogenous environmental pollutants. However, its thermostability and catalytic activity still need to be improved to better adapt to complex environmental conditions. This work elucidates the key mechanisms and important residues of the degradation reaction through multiple computational strategies, establishes a mutation library, and obtains 21 single-point mutation designs. Experimental verification showed that 16 single mutants had enhanced thermostability, with the R89F and L197Y mutants showing the highest increases in thermostability at 135 and 119% relative to the wild-type enzyme, respectively. Additionally, as a result of the higher specific activity of D390Q, it was selected for combination mutagenesis, ultimately resulting in three combination mutants (R89F/L197Y, R89F/D390Q, and R89F/L197Y/ D390Q) with enhanced thermostability and catalytic activity. This study provides a modification approach for constructing efficient enzyme variants through semirational design and can contribute to the development of control technologies for emerging pollutants.

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“…Several pharmaceutically active compounds (PACs) and heavy metals are present in wastewater streams. PACs have been greatly used to prevent and treat diseases affecting humans and animals in the fields of disinfection, aquaculture husbandry, disease diagnosis, epidemic prevention, disease treatment, and animal cultivation [ 7 , 8 ]. PACs have a complex and stable structure, low volatility, varying hydrophobicities among compounds, and their occurrence at trace levels, making their removal difficult using most of the available conventional treatment processes [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…PACs have a complex and stable structure, low volatility, varying hydrophobicities among compounds, and their occurrence at trace levels, making their removal difficult using most of the available conventional treatment processes [ 9 ]. PACs (antibiotics) presence helps in the development of antibacterial resistance genes and thus are responsible in emergence of super-bacteria which has been considered as one of the emerging concern from the past few decades [ 8–12 ]. For example, diclofenac is said to cause antiovulatory effects on aquatic vertebrates, while the presence of ciprofloxacin may affect pathway of photosynthesis in higher plants which result in morphological abnormalities or growth inhibition [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

A comprehensive review on the use of algal-bacterial systems for wastewater treatment with emphasis on nutrient and micropollutant removal

et al. 2022

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The scarcity of water resources and environmental pollution have highlighted the need for sustainable wastewater treatment. Existing conventional treatment systems are energy-intensive and not always able to meet stringent disposal standards. Recently, algal-bacterial systems have emerged as environmentally friendly sustainable processes for wastewater treatment and resource recovery. The algal-bacterial systems work on the principle of the symbiotic relationship between algae and bacteria. This paper comprehensively discusses the most recent studies on algal-bacterial systems for wastewater treatment, factors affecting the treatment, and aspects of resource recovery from the biomass. The algal-bacterial interaction includes cell-to-cell communication, substrate exchange, and horizontal gene transfer. The quorum sensing (QS) molecules and their effects on algal–bacterial interactions are briefly discussed. The effect of the factors such as pH, temperature, C/N/P ratio, light intensity, and external aeration on the algal-bacterial systems have been discussed. An overview of the modeling aspects of algal-bacterial systems has been provided. The algal-bacterial systems have the potential for removing micropollutants because of the diverse possible interactions between algae-bacteria. The removal mechanisms of micropollutants – sorption, biodegradation, and photodegradation, have been reviewed. The harvesting methods and resource recovery aspects have been presented. The major challenges associated with algal-bacterial systems for real scale implementation and future perspectives have been discussed. Integrating wastewater treatment with the algal biorefinery concept reduces the overall waste component in a wastewater treatment system by converting the biomass into a useful product, resulting in a sustainable system that contributes to the circular bioeconomy.

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Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China

Cited by 19 publications

References 53 publications

Tetracycline Removal from Water by Adsorption on Geomaterial, Activated Carbon and Clay Adsorbents

Tetracycline Removal from Water by Adsorption on Geomaterial, Activated Carbon and Clay Adsorbents

Semirational Design Strategy To Enhance the Thermostability and Catalytic Activity of Cytochrome P450 105D7 for the Degradation of the Pharmaceutically Active Compounds: Diclofenac

A comprehensive review on the use of algal-bacterial systems for wastewater treatment with emphasis on nutrient and micropollutant removal

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