Pharmacognostic Screening, Phytochemical Evaluation and In— Vitro free radical Scavenging Activity of Acacia leucophloea Root

Jhade, Deenanath; Jain, Sachin; Jain, Ankit; Sharma, Praveen Kumar

doi:10.1016/s2221-1691(12)60261-5

Cited by 10 publications

(8 citation statements)

References 9 publications

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“…The results show that butanol extract of R. dentatus may have hydrogen donors thus scavenging the free radical DPPH, with the highest scavenging activity than the other plant extracts, which may be attributed to the content of total phenolic compounds in them. The extracts of this plant scavenged free radicals in a dose-dependent manner corresponding with the results of various research works [39][40][41] showing that the plant metabolites such as flavonoids, tannins, catechins and other phenolic compounds possess antioxidant activity. The highest superoxide anion radical scavenging activity of butanol and aqueous extract of R. dentatus corroborates with the results of Jayasri et al [42] .…”

Section: Discussionsupporting

confidence: 76%

Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Nisa

Kamili

Bandh

et al. 2013

Asian Pacific Journal of Tropical Disease

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Section: Discussionsupporting

confidence: 76%

Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Nisa

Kamili

Bandh

et al. 2013

Asian Pacific Journal of Tropical Disease

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“…12 The bark of the thorny tropical and subtropical tree A. leucophloea is an important component in the Indian traditional medicine system, where it is used for various treatments, including wound care. 13 The extracts from this bark are found to contain various bioactive components 14 that not only scientifically validate their use in traditional medicine, but also the study of their participation in self-assembling and capping metal NPs. 2 …”

Section: Discussionmentioning

confidence: 88%

“…13 The aqueous extract of the tree contains phytochemicals such as amino acids, alkaloids, carbohydrates, flavonoids, glycosides, steroids, and tannins, whereas the ethanolic extract is found to contain amino acids, alkaloids, glycosides, flavonoids, tannins, and steroids. 14 The tree extracts have also been found to contain phytoconstituents such as n-hexacosanol, b-amyrin, b-sitosterol, and tannin as major compounds. The presence of these biogenic multifunctional molecules assists in the self-assembly and capping of the metal NPs formed, thereby allowing a measure of shape control during metal ion reduction.…”

mentioning

confidence: 99%

Biosynthesis of silver nanoparticles using Acacia leucophloea extract and their antibacterial activity

Murugan¹,

Balakrishnan²,

Duraisamy³

et al. 2014

IJN

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The immense potential of nanobiotechnology makes it an intensely researched field in modern medicine. Green nanomaterial synthesis techniques for medicinal applications are desired because of their biocompatibility and lack of toxic byproducts. We report the toxic byproducts free phytosynthesis of stable silver nanoparticles (AgNPs) using the bark extract of the traditional medicinal plant Acacia leucophloea (Fabaceae). Visual observation, ultraviolet–visible spectroscopy, and transmission electron microscopy (TEM) were used to characterize the synthesized AgNPs. The visible yellow-brown color formation and surface plasmon resonance at 440 nm indicates the biosynthesis of AgNP. The TEM images show polydisperse, mostly spherical AgNP particles of 17–29 nm. Fourier transform infrared spectroscopy revealed that primary amines, aldehyde/ketone, aromatic, azo, and nitro compounds of the A. leucophloea extract may participate in the bioreduction and capping of the formed AgNPs. X-ray diffraction confirmed the crystallinity of the AgNPs. The in vitro agar well diffusion method confirmed the potential antibacterial activity of the plant extract and synthesized AgNPs against the common bacterial pathogens Staphylococcus aureus (MTCC 737), Bacillus cereus (MTCC 1272), Listeria monocytogenes (MTCC 657), and Shigella flexneri (MTCC 1475). This research combines the inherent antimicrobial activity of silver metals with the A. leucophloea extract, yielding antibacterial activity-enhanced AgNPs. This new biomimetic approach using traditional medicinal plant ( A. leucophloea ) barks to synthesize biocompatible antibacterial AgNPs could easily be scaled up for additional biomedical applications. These polydisperse AgNPs green-synthesized via A. leucophloea bark extract can readily be used in many applications not requiring high uniformity in particle size or shape.

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“…To date, antidiabetic, antidiarrheal, antihyperlipidemic, antipyretic, wound healing, antibacterial, antidementia, antifungal, antiinflammatory, antioxidant, antiplatelet, and bronchorelaxant activities have been scientifically demonstrated for different parts of this plant species (Bobade 2020;Doss et al 2012;Gupta et al 2011Gupta et al , 2012Imram et al 2014;Imran et al 2011Imran et al , 2012Jhade et al 2012;Koppula and Koppula 2012;Madhavi et al 2014;Shahid and Firdous 2012;Sowndhararajan et al 2016;Sulaiman et al 2013;Suriyamoorthy et al 2012;Zia-Ul-Haq et al 2013). Among these reported bioactivities, antibacterial and antioxidant activities have the most number of published works.…”

Section: Reported Bioactivities Of Various Parts Of V Leucophloeamentioning

confidence: 99%

“…An investigation carried out by Jhade et al (2012) unveiled that aqueous, ethanol, and petroleum ether extracts of root at 50 µg/ml concentration showed antioxidant activities in superoxide radical scavenging assay. Ascorbic acid was employed as a standard drug in this investigation.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Bioactivities of extracts and isolated compounds of Vachellia leucophloea (Roxb.) Maslin, Seigler & Ebinger

Sathasivampillai¹,

Sebastian

2021

Bulletin of Biotechnology

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Vachellia leucophloea (Roxb.) Maslin, Seigler & Ebinger is a tree that fits into the Fabaceae family. V. leucophloea has been applied to heal including bronchitis, diabetes, high cholesterol, leprosy, and snakebite. Phytochemicals including betulinic acid-3-O-β-d-maltoside; Δ 7avenasterol; leucophleol; leucophleoxol; and leucoxol; have been isolated from bark, root, and leaf of this plant species. This systematic review article purposes to evaluate, outline, and document the bioactivities associated with available researches involving V. leucophloea. PubMed, Semantic Scholar, Scopus, ScienceDirect, and Web of Science electronic records were employed to find the applicable available works from 1900 to June 2021. So far, in vivo and in vitro scientific evidence is presently existing for several bioactivities. To date, antidiabetic, antidiarrheal, antihyperlipidemic, antipyretic, wound healing, antibacterial, antidementia, antifungal, antiinflammatory, antioxidant, antiplatelet, and bronchorelaxant activities have been scientifically demonstrated for different parts of this plant species. Only an antidiabetic compound {(-)-Fisetinidol-(4α,8)-[(-)-fisetinidol-(4α,6)]-(+)-catechin} has been isolated from this plant species. Further in vitro, in vivo, and clinical studies of various traditional medicinal uses of V. leucophloea should be investigated as well as the bioactive compounds should be identified.

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Pharmacognostic Screening, Phytochemical Evaluation and In— Vitro free radical Scavenging Activity of Acacia leucophloea Root

Cited by 10 publications

References 9 publications

Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Biosynthesis of silver nanoparticles using Acacia leucophloea extract and their antibacterial activity

Bioactivities of extracts and isolated compounds of Vachellia leucophloea (Roxb.) Maslin, Seigler & Ebinger

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