The leaves of Coriandrum sativum commonly known as Cilantro and Petroselinum crispum commonly known as Parsley, family Apiaceae, have several health benefit effects. Most of the people, confused while buying these leaves. In the present study, comparative morphological, microscopic, fluorescence, TLC, and phytochemical parameters, comparative assessment of phenolic and flavonoid contents and in-vitro antioxidant activity of C. sativum and P. crispum leaves were carried out using standard methods. The leaves of these plants are morphologically similar, except other characteristics such as smells, number of lobes and serrate. The microscopic study showed the presence of different types of stomata, epidermis, fibers, and trichrome. Comparative fluorescence, ash content, LOD, and extractive content study were shown the distinct features. The total phenols and flavonoids of the leaves of P. crispum were higher than the leaves of C. sativum, and its antioxidant activity was also stronger than the leaves of C. sativum. The present comparative study reports the first time and can be useful for the identification or authentication of P. crispum and C. sativum leaves or its powder. The in-vitro study proved these edible green leaves may be useful for the dietary supplements.