Pharmacognostical and Preliminary Phytochemical Evaluation of Cordia sebestena L.

Abstract

Background: Cordia sebestena L. belongs to family Boraginaceae is commonly known as "Geiger Tree" in Indonesia, it is generally found in Indonesia included Jakarta, and many other countries. Some researchers have revealed the presence of several pharmacology activities. Thus this study is an attempt to present an overview of pharmacognostic and phytochemical evaluation reported on this plant. Objective: In the present investigation, various pharmacognostic standards have been investigated to prove the authenticity of the plant for the claimed traditional uses. This will help in the identification of powder drug prior to using in medicine. Methods: Macroscopic, microscopic and physicochemical evaluation, of the drug was performed using standardized procedures as mentioned in the WHO and Indonesian Herb Pharmaco poeia guidelines.Thin layer chromatography profile was done using some different mobile phase system to the identification of the drug. Results: The physicochemical parameters such as moisture content, ethanol-and water-soluble extractive, total ash, acidinsoluble ash value, were determined. Phytochemical screening showed the presence of alkaloids, flavonoids, phenols, saponins, tannins, steroids, terpenoids in the ethanolic extracts of leaf of this plant. The TLC profile of n-hexane, dichloromethane and methanol extract were carried out 5, 7 and 2 spots respectively. Conclusion: The present study on pharmacognostical, physicochemical and phytochemical standards could be useful information for authentication and preparation monograph for C.sebestena.

Total Phenolic Content and Antioxidant Activity of Different Extracts of Cordia sebestena L. Leaves

“…Phytochemical screening results in this study are following previous studies by Hanani et al 21 that ethanolic extract of C. sebestena leaves showed alkaloids, phenols, flavonoids, tannins, saponin, steroids, and terpenoids. It can be implied that the phytochemical compounds in C. sebestena leaves dissolved better in 70% ethanol solvent.…”

“…Meanwhile, EECS shows a high total ash value of 16.31%. Hanani et al 21 reported that ash values of powdered leaves of C. sebestena were found 13.6%. The amount and composition of ash remaining after the combustion of plant material vary considerably according to the part of the plant, treatment, age, location etc.…”

Preliminary Phytochemical Evaluation, Isolation and Spectroscopic Characterization of Constituents in the Dried Extracts of the Whole Plant Crotalaria Biflora (L)

“…It may be due to their high polarity 13 . TLC profiling of crude extracts is crucial one for the development of quality parameters 20 . In this study, five pure compounds were isolated by TLC and two among them were characterized by spectral studies.…”

Ochna kirkii Oliv: Pharmacognostical Evaluation, Phytochemical Screening, and Total Phenolic Content

“…Preparing for powder microscopic of the plants part were observed under the microscope and photographed. The procedure for the microscopic study was described in Indonesian Herb Pharmacopoeia 10 and Hanani et al 11…”

“…Strong acids, alkalis and organic solvents were added and observed under the daylight and ultraviolet light at 254 nm and 366 nm. 11,15 Thin layer chromatography profile All fractions were analyzed for the chromatographic profile using TLC (silica gel 60 GF 254 ) with different solvents. Each fraction was solved with suitable solvents and spotted using the micro-pipette in the silica plate surface.…”