Pharmacokinetics of cefotaxime in dialysis patients

Hemofiltration: treating and preventing infection

“…For cefotaxime, one study which measured both cefotaxime and its active metabolite desacetylcefotaxime in eight patients with renal failure on CAVH, a dose of 1 g every 24 h was recommended [42]. Andrassy suggested that dosage adjustments for cefotaxime should be based on renal function with no adjustments during CH [43].…”