2005
DOI: 10.1016/j.toxicon.2005.07.016
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Pharmacological and structural characterization of a novel phospholipase A2 from Micrurus dumerilii carinicauda venom

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Cited by 37 publications
(34 citation statements)
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“…Further evidence for a presynaptic involvement was the marked increase in quantal content within five minutes after the extract addition to the preparations. Dal Belo et al [11] observed a similar increase in the quantal content of PND preparations after ten-minute incubation with MiDCA1, a toxin isolated from coral snake ( Micrurus dumerilli carinicauda ) venom, and concluded that a presynaptic action was involved.…”
Section: Resultsmentioning
confidence: 86%
See 1 more Smart Citation
“…Further evidence for a presynaptic involvement was the marked increase in quantal content within five minutes after the extract addition to the preparations. Dal Belo et al [11] observed a similar increase in the quantal content of PND preparations after ten-minute incubation with MiDCA1, a toxin isolated from coral snake ( Micrurus dumerilli carinicauda ) venom, and concluded that a presynaptic action was involved.…”
Section: Resultsmentioning
confidence: 86%
“…The quantal content (QC) was estimated as the quotient between the squared average of the EPPs and the variance of the EPPs (indirect method), as described by Dal Belo et al [11]. …”
Section: Methodsmentioning
confidence: 99%
“…In the Americas, the snakes known as coral snakes or corals are those belonging to the genus Leptomicrurus, Micrurus and Micruroides, which are representatives of the Elapidae family in this part of the world (Urdaneta et al, 2004;Dal Belo et al, 2005). This genus presents a greater variability of species in the areas surrounding the equator (Salazar et al, 2011).…”
Section: Introductionmentioning
confidence: 99%
“…Figure 3A shows a representative record of the neuromuscular blockade caused by a venom concentration of 10 µg/mL and contracture responses to ACh and KCl before and after venom treatment. The decrease of the twitch tension in avian neuromuscular preparations caused by Elapidic venoms has been previously shown [13,21,22,23,24,25]. At these preparations, the muscle-type nicotinic receptors are distributed alongside the muscle fiber characterizing the multiple neuromuscular junctions [26].…”
Section: Resultsmentioning
confidence: 99%