P hthalocyanines (Pcs) can be used many different applications such as gas sensors, electrochromic devices, photovoltaic cells and photodynamic therapy (PDT), due to their 18-π planar conjugate electron system [1][2][3][4]. Therefore synthesizing Pcs having different groups play a vital role in promoting these high technologies.These macrocyclic compounds are ideal building blocks for applications when they are modified with groups in the desired properties. For this reason, substitution of Pcs either on peripheral/nonperipheral or axial positions has vital importance for their utilizations. Furthermore, the solubility of Pc derivatives plays a critical role in order to use in all those applications. Phthalocyanines that unsubstituted are not soluble in common organic solvents due to the aggregation. These compounds can be made soluble in organic solvents by integration of substituents in the periphery/non-periphery of Pc core, thus increasing their electrochemical and catalysis applications. [5]. 1,2,4-Triazole derivatives are one of the key organic compound class have an important functions in biological applications. It's known that some of 1,2,4-triazoles exhibit biological trenchancy e.g. antifungal, anti microbial, anti viral, anti tubercular,