Pharmacomechanical thrombolysis with a rotator thrombolysis device in iliofemoral deep venous thrombosis

Karahan, Oğuz; Kutas, H Barıs; Gürbüz, Orçun; Tezcan, Orhan; Çalışkan, Ahmet; Yavuz, Celal; Demirtaş, Sinan; Mavitaş, Binali

doi:10.1177/1708538115612637

Cited by 10 publications

(13 citation statements)

References 17 publications

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“…The mean follow-up time was 12.3 months (range, 1-82 months). Four different categories of thrombectomy devices were used among the included studies: rheolytic devices, [6][7][8][9][10][11] aspiration devices, [12][13][14][15][16] rotational devices, [16][17][18][19][20][21] and ultrasound-enhanced thrombolysis devices. 14 They aimed to achieve transcatheter removal of thrombi via different mechanical means.…”

Section: Resultsmentioning

confidence: 99%

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

Pc¹,

Chan²,

Law³

et al. 2019

Hong Kong Med J

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Section: Resultsmentioning

confidence: 99%

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

Pc¹,

Chan²,

Law³

et al. 2019

Hong Kong Med J

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“…A study described pharmacomechanical thrombolysis with a rotator thrombolysis device in iliofemoral deep venous thrombosis in 67 patients. 18 Immediate total recanalization was conducted in all patients, the leg diameters returned to normal ranges in the early postoperative period, and hospital mortality or severe complications were not detected. In general, the ACCP guidelines recommend anticoagulant alone over thrombolysis or catheter-assisted thrombus removal including in patients with acute DVT and PE.…”

Section: Management Of Proximal Dvt and Symptomatic Pementioning

confidence: 90%

An Algorithmic Approach to Management of Venous Thromboembolism

Dhakal

Gundabolu

Bhatt

2016

Clin Appl Thromb Hemost

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Venous thromboembolism (VTE) is associated with significant morbidity and mortality. Factors such as the presence of transient risk factors for VTE, risk of bleeding, and location of deep vein thrombosis (DVT) determine the duration of anticoagulation. Extended anticoagulation is offered to patients with unprovoked pulmonary embolism (PE) or proximal DVT and a low risk of bleeding. Anticoagulation for 3 months is advised in patients with provoked DVT or PE, high risk of bleeding, and isolated distal or upper extremity DVT. In patients with unprovoked PE or proximal DVT and a low risk of bleeding, who want to stop anticoagulation after 3 months, further risk stratification is necessary. Clinical scoring system, and thrombophilia testing otherwise not routinely performed, may be considered to measure risk of annual recurrence in such cases. Short-term anticoagulation may be considered in subsegmental PE and superficial vein thrombosis, particularly if patients are at low risk of bleeding and have persistent risk factors for recurrent VTE. In cases of catheter-associated thrombosis, the catheter need not be removed routinely, and the patient may be anticoagulated for 3 months or longer if the catheter is maintained in patients with cancer. Extensive screening for occult cancer in cases of unprovoked VTE is not beneficial. New oral anticoagulants such as apixaban, rivaroxaban, or dabigatran may be preferred to vitamin K antagonists in patients without cancer or renal failure, more so after the development of reversal agents such as idarucizumab and andexanet alfa.

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“…Early thrombus removal has been advocated to prevent PTS providing venous tract open and healthy venous valve competence 9 . Several studies have shown that CDT with or without an additional procedure such as US-accelerated, pharmacomechanic-assisted intervention is effective to obtain a dramatic reduction in the PTS incidence 6,7,10,11 . However, in their study, Kim et al 12 reported that CDT was unable to prevent PTS and its efficacy was controversial.…”

Section: Discussionmentioning

confidence: 99%

Popliteal ven tutulumu olmayan akut iliofemoral ven trombozunun ultrasonla hızlandırılmış kateter aracılı trombolitik tedavisi: erken ve orta dönem sonuçlar

Kubat

Ünal²,

Keskin³

et al. 2019

Cukurova Medical Journal

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The aim of this study was to assess early and midterm results of the patients undergoing ultrasoundaccelerated catheter-directed thrombolysis for the treatment of acute iliofemoral deep venous thrombosis without popliteal vein thrombosis. Materials and Methods: A total of 18 patients (11 males, 7 females; mean age: 51.89±16.29 years; range, 16 to 72 years) who were diagnosed with acute iliofemoral deep vein thrombosis between November 2014 and December 2015 were included in this retrospective cross-sectional study. Results: Complete thrombolysis was successful in 88.9% (n=16) and in % 11.1 (n=2) patients with partial clot lysis. No pulmonary embolism was seen, while bleeding at the catheter-insertion site was observed in one patient. In another patient, underlying lesions were successfully treated with balloon angioplasty. The mean follow-up was 31.56±3.35 (range, 25 to 37 months). Duplex ultrasound was performed at one month, six months, one year, and two years following intervention and the iliac vein patency rate was found to be 100%, while superficial femoral vein insufficiency was in 5.6% (n=1), 11.1% (n=2), 16.2% (n=3), and 16.2% (n=3), respectively. Conclusion: Based on our findings, ultrasoundaccelerated catheter-directed thrombolysis is a safe and effective method for carefully selected patients with acute iliofemoral deep vein thrombosis without popliteal vein thrombosis.

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Pharmacomechanical thrombolysis with a rotator thrombolysis device in iliofemoral deep venous thrombosis

Abstract: New thrombolytic devices seem to reduce in-hospital mortality risks and may potentially decrease post-thrombotic morbidity.

Cited by 10 publications

References 17 publications

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

An Algorithmic Approach to Management of Venous Thromboembolism

Popliteal ven tutulumu olmayan akut iliofemoral ven trombozunun ultrasonla hızlandırılmış kateter aracılı trombolitik tedavisi: erken ve orta dönem sonuçlar

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