Pharmakokinetische und pharmakodynamische Modellierung bei Kinderarzneimitteln: Schwerpunkt Physiologie-basiertes pharmakokinetisches Simulieren

Läer, Stephanie

doi:10.1016/j.zefq.2019.03.003

Cited by 1 publication

(1 citation statement)

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“…The concept of precision medicine proposes that clinical cancer diagnosis and treatment require precise information, such as the location and size of a tumor and whether or not the signs of metastasis exist. However, advancements in tumor imaging have been relatively slow due to the availability of poor pharmacokinetic profiles or the high cost of clinical development of molecular imaging agents [54].…”

Section: Nano-diagnostic and Therapeutic Technologymentioning

confidence: 99%

Review of the Application of Dual Drug Delivery Nanotheranostic Agents in the Diagnosis and Treatment of Liver Cancer

Han,

Du,

Zhu

et al. 2023

Molecules

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Liver cancer has high incidence and mortality rates and its treatment generally requires the use of a combination treatment strategy. Therefore, the early detection and diagnosis of liver cancer is crucial to achieving the best treatment effect. In addition, it is imperative to explore multimodal combination therapy for liver cancer treatment and the synergistic effect of two liver cancer treatment drugs while preventing drug resistance and drug side effects to maximize the achievable therapeutic effect. Gold nanoparticles are used widely in applications related to optical imaging, CT imaging, MRI imaging, biomarkers, targeted drug therapy, etc., and serve as an advanced platform for integrated application in the nano-diagnosis and treatment of diseases. Dual-drug-delivery nano-diagnostic and therapeutic agents have drawn great interest in current times. Therefore, the present report aims to review the effectiveness of dual-drug-delivery nano-diagnostic and therapeutic agents in the field of anti-tumor therapy from the particular perspective of liver cancer diagnosis and treatment.

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Section: Nano-diagnostic and Therapeutic Technologymentioning

confidence: 99%